Harmful or harmless: Biological effects of marennine on marine organisms

[en] Marennine is a water-soluble blue-green pigment produced by the marine diatom Haslea ostrearia. The diatom and its pigment are well known from oyster farming areas as the source of the greening of oyster gills, a natural process increasing their market value in Western France. Blooms of blue Haslea are also present outside oyster ponds and hence marine organisms can be exposed, periodically and locally, to significant amounts of marennine in natural environments. Due to its demonstrated antibacterial activities against marine pathogenic bacteria (e.g. Vibrio) and possible prophylactic effects toward bivalve larvae, marennine is of special interest for the aqua-culture industry, especially bivalve hatcheries. The present study aimed to provide new insights into the effects of marennine on a large spectrum of marine organisms belonging to different phyla, including species of aquaculture interest and organisms frequently employed in standardised ecotoxicological assays. Different active solutions containing marennine were tested: partially purified Extracellular Marennine (EMn), and concentrated solutions of marennine present in H. ostrearia culture supernatant; the Blue Water (BW) and a new process called Concentrated Supernatant (CS). Biological effects were meanwhile demonstrated in invertebrate species for the three marennine-based solutions at the highest concentrations tested (e.g., decrease of fertilization success, delay of embryonic developmental stages or larval mortality). Exposure to low concentrations did not impact larval survival or development and even tended to enhance larval physiological state. Furthermore, no effects of marennine were observed on the fish gill cell line tested. Marennine could be viewed as a Jekyll and Hyde molecule, which possibly affects the earliest stages of development of some organisms but with no direct impacts on adults. Our results emphasize the need to determine dosages that optimize beneficial effects and critical concentrations not to be exceeded before considering the use of marennine in bivalve or fish hatcheries.

Disciplines :

Microbiology
Environmental sciences & ecology
Aquatic sciences & oceanology
Phytobiology (plant sciences, forestry, mycology...)

Author, co-author :

Falaise, Charlotte

Cormier, Patrick

Tremblay, Réjean

Audet, Céline

Deschênes, Jean-Sebastien

Turcotte, François

François, Cyrille

Seger, Andreas

Hallegraeff, Gustaaf

Linquist, Niels

More authors (4 more)

Language :

English

Title :

Harmful or harmless: Biological effects of marennine on marine organisms

Publication date :

21 January 2019

Journal title :

Aquatic Toxicology

ISSN :

0166-445X

eISSN :

1879-1514

Publisher :

Elsevier

Volume :

209

Pages :

13-25

Peer reviewed :

Peer Reviewed verified by ORBi

European Projects :

H2020 - 734708 - GHaNA - The Genus Haslea, New marine resources for blue biotechnology and Aquaculture

Name of the research project :

The Genus Haslea, New marine resources for blue biotechnology and Aquaculture, grant agreement No [734708/ GHANA/H2020-MSCA-RISE- 2016]

Funders :

CE - Commission Européenne [BE]

Available on ORBi :

since 03 September 2019

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