Article (Scientific journals)
Neurostimulation in chronic cluster headache.
Magis, Delphine; Schoenen, Jean
2008In Current Pain and Headache Reports, 12 (2), p. 145-53
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Keywords :
Cluster Headache/physiopathology/therapy; Deep Brain Stimulation/methods; Electric Stimulation Therapy/methods; Humans; Vagus Nerve/physiology
Abstract :
[en] About 1% of all chronic cluster headache patients become intractable (iCCH; ie, they are refractory to adequate regimens of all established preventive drugs). Various lesional interventions have been attempted in these patients, none with lasting benefits. In recent years, nondestructive neurostimulation methods have raised new hope. Hypothalamic deep brain stimulation (hDBS) acts rather rapidly and has durable efficacy, but it is not without risk. Occipital nerve stimulation (ONS) was studied in two trials that included 17 iCCH patients. Clinical efficacy was found to be very satisfactory by most patients and investigators. Although slightly less efficacious than hDBS, ONS has the advantage of being harmless and reversible. At this stage, it should be the preferred first-line invasive therapy for iCCH. Recent case reports mention efficacy of supraorbital and vagus nerve stimulation. Whether these neurostimulation methods have a place in the management of iCCH patients remains to be determined.
Disciplines :
Neurosciences & behavior
Neurology
Author, co-author :
Magis, Delphine ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Schoenen, Jean  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Neuro-anatomie
Language :
English
Title :
Neurostimulation in chronic cluster headache.
Publication date :
2008
Journal title :
Current Pain and Headache Reports
ISSN :
1531-3433
eISSN :
1534-3081
Publisher :
Current Science, United States
Volume :
12
Issue :
2
Pages :
145-53
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 04 March 2011

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