[en] In genetics and genomics, more and more researchers get interested in modelling
continuous cellular differentiations thanks to “gene activities” (synthesis
of RNA). In this talk, we present a recent mathematical model, named RNA Velocity,
which aims to compute vectors indicating the direction of developments
inside large samples of cells. We also describe some perspectives for this tool
in the detection of genes responsible of specific cellular specializations, which
constitutes the core of our research project in GIGA (ULiège) for the next years.
Disciplines :
Mathematics
Author, co-author :
Demeulenaere, Loïc ; Université de Liège - ULiège > Medical Genomics-Unit of Animal Genomics
Language :
English
Title :
RNA Velocity: a mathematical model to predict cellular differentiations
Publication date :
26 June 2019
Event name :
Comprehensible seminars of the Institute of Mathematics of the University of Liège