Article (Scientific journals)
RISK FACTORS FOR SKIN INFECTIONS IN MYCOSIS FUNGOIDES
LEBAS, Eve; ARRESE ESTRADA, Jorge; NIKKELS, Arjen
2017In Dermatology, 232 (6), p. 731-737
 

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Keywords :
Herpes simplex virus; Staphylococcus; Infection; Skin; Mycosis fungoides; Cellulitis; Cutaneous T-cell lymphoma
Abstract :
[en] Background: Mycosis fungoides (MF) is the most frequent type of primary cutaneous natural killer and T-cell lymphoma. MF-required immunosuppressive therapies and MF-related immunosuppressive characteristics render patients with MF more prone to infections. Aim: To describe the clinical features of cutaneous infections observed in MF patients. Materials and Methods: A series of 56 MF patients were followed prospectively over 3 years and screened for cutaneous infections. Type of Study: Prospective observational study. Results: Four herpes simplex virus type-I (HSV-I), 2 staphylococcal (S. aureus) impetiginizations and 2 Malassezia infections were detected in single isolated plaque/patch stage MF as well as 1 varicella zoster virus infection (herpes zoster, HZ) and 2 cases of cellulitis in 10 patients. All patients presented advanced MF. All the diagnoses were delayed due to atypical clinical presentations. Conclusions: Patients with advanced MF should be particularly monitored for skin infections, especially by HSV and S. aureus. Unexplained exacerbation or the sudden appearance of oozing or ulcerations in MF lesions should initiate a search for viral or bacterial agents. Cellulitis and HZ can be severer and prolonged in MF patients.
Disciplines :
Dermatology
Author, co-author :
LEBAS, Eve ;  Centre Hospitalier Universitaire de Liège - CHU > Service de dermatologie
ARRESE ESTRADA, Jorge ;  Centre Hospitalier Universitaire de Liège - CHU > Service dermatopathologie
NIKKELS, Arjen ;  Centre Hospitalier Universitaire de Liège - CHU > Service de dermatologie
Language :
English
Title :
RISK FACTORS FOR SKIN INFECTIONS IN MYCOSIS FUNGOIDES
Publication date :
2017
Journal title :
Dermatology
ISSN :
1018-8665
eISSN :
1421-9832
Publisher :
KARGER
Volume :
232
Issue :
6
Pages :
731-737
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