Article (Scientific journals)
Use of Recombinant Vaccinia-Rabies Virus for Oral Vaccination of Fox Cubs (Vulpes Vulpes, L) against Rabies
Brochier, B. M.; Languet, B.; Blancou, J. et al.
1988In Veterinary Microbiology, 18 (2), p. 103-8
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Abstract :
[en] Thirteen fox cubs were orally administered 10(7.2) plaque-forming units of live vaccinia-rabies glycoprotein recombinant virus. On Day 28 post-vaccination, all but 1 cub had produced rabies virus antibodies. Twelve animals were intramuscularly inoculated with 10(3.2) mouse intracerebral LD50 of rabies virus suspension on Days 33 (5 foxes), 180 (4 foxes) or 360 (3 foxes) after vaccination. Eleven of them resisted rabies challenge. Unvaccinated foxes, either put in contact with 1 vaccinated animal or used as controls, died after challenge applied on Day 33. The absence of horizontal transmission of this vaccine strain and its innocuity to cubs were also demonstrated.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Brochier, B. M.;  Université de Liège - ULiège > Faculté de Médecine vétérinaire
Languet, B.;  Rhône-Mérieux (Lyon)
Blancou, J.;  Centre national d'études sur la rage et la pathologie des animaux sauvages (Malzéville)
Kieny, M. P.;  Transgene (Strasbourg)
Lecocq, J. P.;  Transgene (Strasbourg)
Costy, F.;  Institut Pasteur du Brabant
Desmettre, P.;  Rhône-Mérieux (Lyon)
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Faculté de Médecine vétérinaire
Language :
English
Title :
Use of Recombinant Vaccinia-Rabies Virus for Oral Vaccination of Fox Cubs (Vulpes Vulpes, L) against Rabies
Publication date :
October 1988
Journal title :
Veterinary Microbiology
ISSN :
0378-1135
eISSN :
1873-2542
Publisher :
Elsevier, Netherlands
Volume :
18
Issue :
2
Pages :
103-8
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 01 June 2019

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