Article (Scientific journals)
Cell migration promotes dynamic cellular interactions to control cerebral cortex morphogenesis.
Gomes Da Silva, Carla; Peyre, Elise; Nguyen, Laurent
2019In Nature Reviews. Neuroscience
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Abstract :
[en] The cerebral cortex is an evolutionarily advanced brain structure that computes higher motor, sensory and cognitive functions. Its complex organization reflects the exquisite cell migration and differentiation patterns that take place during embryogenesis. Recent evidence supports an essential role for cell migration in shaping the developing cerebral cortex via direct cellular contacts and spatially organized diffusible cues that regulate the establishment of its cytoarchitecture and function. Identifying the nature of the crosstalk between cell populations at play during brain development is key to understanding how cerebral cortical morphogenesis proceeds in health and disease.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Gomes Da Silva, Carla ;  Université de Liège - ULiège > Neurosciences-Molecular Regulation of Neurogenesis
Peyre, Elise
Nguyen, Laurent  ;  Université de Liège - ULiège > Neurosciences-Molecular Regulation of Neurogenesis
Language :
English
Title :
Cell migration promotes dynamic cellular interactions to control cerebral cortex morphogenesis.
Publication date :
2019
Journal title :
Nature Reviews. Neuroscience
ISSN :
1471-003X
eISSN :
1471-0048
Publisher :
Nature Publishing Group, United Kingdom
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 April 2019

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