Poster (Scientific congresses and symposiums)
Macrophage activation syndrome secondary to a CMV infection in a neonate
ADOUANE, Linda; Florkin, Benoît; Tribolet, Sophie et al.
2017Congrès de la Société Belge de Pédiatrie
 

Files


Full Text
BVKSBP_Abstract_239.pdf
Publisher postprint (2.96 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Macrophage activation syndrome; Haemophagocytosis
Abstract :
[en] Macrophage activation syndrome is a rare and potentially fatal systemic immunologic disorder. It generally occurs in patients who encounters specific pathogens in the context of preexisting congenital or acquired immune deficiencies. It is associated with a reported 20-30% mortality rates with a much better prognosis in secondary disease. The earlier recognition of its clinical features and treatment are critical. In our patient, immunological workup showed no indication of a familial HLH. Genetic analysis for homozygocy showed that all known genes for FHLH or secondary HLH to metabolic diseases were heterozygous. X-linked forms were excluded. We concluded that CMV was probably the causative agent of secondary macrophage activation syndrome. Further follow-up comforts this idea.
Disciplines :
Pediatrics
Author, co-author :
ADOUANE, Linda ;  Université de Liège - ULiège
Florkin, Benoît ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Tribolet, Sophie ;  Centre Hospitalier Universitaire de Liège - CHU > Département de Pédiatrie > Service néonatologie (CHR)
Henrion, Elisabeth;  Centre Hospitalier Régional de Namur > Département de Pédiatrie > Service de Néonatologie
PIERART, Julie ;  Centre Hospitalier Universitaire de Liège - CHU > Département de Pédiatrie > Service néonatologie (CHR)
Language :
English
Title :
Macrophage activation syndrome secondary to a CMV infection in a neonate
Alternative titles :
[fr] Syndrome d'Activation Macrophagique secondaire à un infection à CMV chez un nouveau-né
Publication date :
2017
Event name :
Congrès de la Société Belge de Pédiatrie
Event date :
23-24/03/17
Available on ORBi :
since 19 March 2019

Statistics


Number of views
102 (8 by ULiège)
Number of downloads
60 (7 by ULiège)

Bibliography


Similar publications



Contact ORBi