Article (Scientific journals)
Antimicrobial peptide encapsulation and sustained release from polymer network particles prepared in supercritical carbon dioxide
Parilti, Rahmet; Caprasse, Jérémie; Riva, Raphaël et al.
2018In Journal of Colloid and Interface Science, 532, p. 112-117
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Keywords :
supercritical carbon dioxide; organic nanoparticle
Abstract :
[en] Antimicrobial peptide loaded poly(2-hydroxyethyl methacrylate) particles were synthesized in supercritical carbon dioxide via one-pot free-radical dispersion polymerisation of 2-hydroxyethyl methacrylate and a cross-linker. Discrete particles with a well-defined spherical morphology and a diameter as low as 450 nm have been obtained in mild conditions. The encapsulation and release of the peptide were confirmed by antimicrobial tests that demonstrated for the first time a sustained release of the peptide from poly(2-hydroxyethyl methacrylate) microgels prepared by one-pot dispersion polymerization in supercritical carbon dioxide and then dispersed in water. © 2018
Research center :
CESAM - Complex and Entangled Systems from Atoms to Materials - ULiège
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering
Chemistry
Author, co-author :
Parilti, Rahmet;  University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM) > University of Nottingham, School of Chemistry, UK
Caprasse, Jérémie ;  University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Riva, Raphaël ;  University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Alexandre, Michaël;  Symbiose Biomaterials, Liège, Belgium
Vandegaart, Hélène;  Symbiose Biomaterials, Liège, Belgium
Bebrone, Carine ;  Symbiose Biomaterials, Liège, Belgium
Dupont-Gillain, Christine;  Université catholique de Louvain (UCL), Institute of Condensed Matter and Nanosciences (IMCN), Bio and Soft Matter Division (BSMA)
Howdle, Steven M.;  University of Nottingham, School of Chemistry, UK
Jérôme, Christine  ;  University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Antimicrobial peptide encapsulation and sustained release from polymer network particles prepared in supercritical carbon dioxide
Publication date :
15 December 2018
Journal title :
Journal of Colloid and Interface Science
ISSN :
0021-9797
eISSN :
1095-7103
Publisher :
Academic Press Inc.
Volume :
532
Pages :
112-117
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique
The Erasmus Mundus Joint Doctorate Program in the frame of "Nanofar"
The Walloon Region in the frame of the "Smartdif" project
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since 13 February 2019

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