COOK DL, HALES CN: Intracellular ATP directly blocks K+ channels in pancreatic B cells. Nature (1984) 311:271-273
ALLARD B, LAZDUNSKI M: Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscles cells. Eur. J. Pharmacol. (1993) 236:419-426.
STANDEN NB, QUAYLE JM, DAVIES NW, BRAYDEN JE, HUANG Y, NELSON MT: Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle. Science (1989) 245:177-180.
QUAYLE JM, NELSON MT, STANDEN NB: ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol. Rev. (1997) 77:1165-1232.
BERNARDI HA, FOSSET M, LAZDUNSKI M: Purification and affinity labeling of a brain [3H]-glibenclamide binding protein, a putative neuronal ATP-regulated K+ channel. Proc. Natl. Acad. Sci. USA. (1988) 85:9816-9820.
PETERSEN OH, DUNNE MJ: Regulation of K+ channels plays a crucial role in the control of insulin secretion. Pflügers Arch. (1989) 414:S115-S120.
KOLB HA: Potassium channels in excitable and non-excitable cells. Rev. Physiol. Biochem. Pharmacol. (1990) 15:51-79.
AMOROSO S, SCHMID-ANTOMARCHI H, FOSSET M, LAZDUNSKI M: Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels. Science (1990) 247:852-854.
NICHOLS CG, LEDERER WJ: The regulation of ATP-sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes. J. Physiol. (1990) 423:91-110.
GASSER RN, VAUGHAN-JONES RD: Mechanism of potassium efflux and action potential shortening during ischaemia in isolated mammalian cardiac muscle. J. Physiol. (1990) 431:713-741.
LIU Y, SATO T, O'ROURKE B, MARBAN E: Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection? Circulation (1998) 97:2463-2469.
INAGAKI N, GONOI T, CLEMENT JP et al.: Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science (1995) 270:1166-1170.
BABENKO AP, AGUILAR-BRYAN L, BRYAN J: A view of SUR/Kir6.X KATP channels. Ann. Rev. Physiol. (1998) 60:667-687.
ISOMOTO S, KONDO C, YAMADA M et al.: A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel. J. Biol. Chem. (1996) 271:24321-24324.
INAGAKI N, GONOI T, CLEMENT JP et al.: A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels. Neuron (1996) 16:1011-1017.
LISS B, BRUNS R, ROEPER J: Alternative sulfonylurea receptor expression defines metabolic sensitivity of KATP channels in dopaminergic midbrain neurons. EMBO J. (1999) 18:833-846.
PIROTTE B, FONTAINE J, LEBRUN P: Recent advances in the chemistry of potassium channel openers. Curr. Med. Chem. (1995) 2:573-582.
LEBRUN P, ARKHAMMAR P, ANTOINE M-H, NGUYEN Q-A, BONDO HANSEN J, PIROTTE B: A potent diazoxide analogue activating ATP-sensitive K+ channels and inhibiting insulin release. Diabetologia (2000) 43:723-732.
HANSEN JB, ARKHAMMAR PO, BODVARSDOTTIR TB, WAHL P: Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders. Curr. Med. Chem. (2004) 11:1595-1615.
MIURA T, MIKI T: ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart. Curr. Vasc. Pharmacol. (2003) 1:251-258.
COGHLAN MJ, CARROLL WA, GOPALAKRISHNAN M: Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress. J. Med. Chem. (2001) 44:1627-1653.
ASHCROFT FM, GRIBBLE FM: New windows on the mechanism of action of KATP channel openers. Trends Pharmacol. Sci. (2000) 21:439-445.
GARLID KD, PAUCEK P, YAROV-YAROVOY V et al.: Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection. Circ. Res. (1997) 81:1072-1082.
LEBRUN P, DEVREUX V, HERMANN M, HERCHUELZ A: Similarities between the effects of pinacidil and diazoxide on ionic and secretory events in rat pancreatic islets. J. Pharmacol. Exp. Ther. (1989) 250:1011-1018.
ANTOINE M-H, BERKENBOOM G, FANG Z-Y, FONTAINE J, HERCHUELZ A, LEBRUN P: Mechanical and ionic response of rat aorta to diazoxide. Eur. J. Pharmacol. (1992) 216:299-306.
WANG H, ZHANG YL, TANG XC, FENG HS, GANG H: Targeting ischaemic stroke with a novel opener of ATP-sensitive potassium channels in the brain. Mol. Pharmacol. (2004) 66:1160-1168.
WANG H, LONG CL, ZHANG YL: A new ATP-sensitive potassium channel opener reduces blood pressure and reverses cardiovascular remodeling in experimental hypertension. J. Pharmacol. Exp. Ther. (2005) 312:1326-1333.
NIELSEN FE, BODVARSDOTTIR TB, WORSAAE A et al.: 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP-sensitive potassium channels of pancreatic β-cells, J. Med. Chem. (2002) 45:4171-4187.
PIROTTE B, DE TULLIO P, LEBRUN P et al.: 3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic β cells: a new class of potassium channel openers? J. Med. Chem. (1993) 36:3211-3213.
DE TULLIO P, PIROTTE B, LEBRUN P et al.: 3- and 4-substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1, 1-dioxides as potassium channel openers: synthesis, pharmacological evaluation, and structure-activity relationships. J. Med. Chem. (1996) 39:937-948.
DE TULLIO P, BECKER B, BOVERIE S et al.: Toward tissue-selective pancreatic B cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides. J. Med. Chem. (2003) 46:3342-3353.
PIROTTE B, ANTOINE M-H, DE TULLIO P et al.: A pyridothiadiazine (BPDZ-44) as a new and potent activator of ATP-sensitive K+ channels. Biochem. Pharmacol. (1994) 47:1381-1386.
COSGROVE KE, ANTOINE M-H, LEE AT et al.: BPDZ-154 activates adenosine 5′-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism. J. Clin. Endocrinol. Metab. (2002) 87:4860-4868.
SEBILLE S, DE TULLIO P, BOVERIE S, ANTOINE M-H, LEBRUN P, PIROTTE B: Recent developments in the chemistry of potassium channel activators: the cromakalim analogs. Curr. Med. Chem. (2004) 11:1213-1222.
KOGA H, OHTA M, SATO H, ISHIZAWA T, NABATA H: Design of potent K+ channel openers by pharmacophore model. Bioorg. Med. Chem. Lett. (1993) 3:625-631.
TAKA N. KOGA H. SATO H, ISHIZAWA T, TAKAHASHI T, IMAGAWA J: 6-Substituted 2,2-bis(fluoromethyl)-benzopyran-4-carboxamide K+ channel openers. Bioorg. Med. Chem. (2000) 8:1393-1405.
RAASMAJA A, TALO A, HAIKALA H, NISSINEN E, LINDÉN IB, POHTO P: Biochemical properties of OR-1259, a positive inotropic and vasodilatory compound with an antiarrythmic effect. Adv. Exp. Med. Biol. (1992) 311:423.
KOPUSTINSKIENE DM, POLLESELLO P, SARIS NE: Levosimendan is a mitochondrial K(ATP) channel opener. Eur. J. Pharmacol. (2001) 428:311-314.
