Article (Scientific journals)
Determination of phthalate esters in vegetable oils using direct immersion solid-phase microextraction and fast gas chromatography coupled with triple quadrupole mass spectrometry
Barp, L.; Purcaro, Giorgia; Franchina, Flavio et al.
2015In Analytica Chimica Acta, 887, p. 237-244
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Keywords :
Fast gas chromatography; Phthalates; Solid-phase microextraction; Triple-quadrupole mass spectrometry; Agents; Chromatography; Endocrine disrupters; Esters; Gas chromatography; Gas oils; Ionization of gases; Mass spectrometry; Microchannels; Oils and fats; Potassium compounds; Silicones; Solvents; Spectrometry; Vegetable oils; Direct immersion solid-phase microextraction; Endocrine disrupting chemicals; Polydimethylsiloxane PDMS; Solid phase microextraction method; Extraction; Article; Endocrine Disruptors; Esterification; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Liquid-Liquid Extraction; Phthalic Acids; Plant Oils; Plasticizers; Solid Phase Microextraction
Abstract :
[en] Phthalates are a group of synthetic compounds mainly used as plasticizers, which have been classified as endocrine-disrupting chemicals and potential human-cancer causing agents. They can be found in high amounts in foods, deriving mainly from plastic packaging. The analytical determination of these compounds is very challenging since they are ubiquitous. Therefore, minimization of sample manipulation is highly desirable.The present work exploited the application of a solid-phase microextraction method for the analysis of phthalates in vegetable oil. A preliminary comparison between a polydimethylsiloxane (PDMS) and a Carbopack Z/PDMS fiber was carried out both in the headspace and direct immersion extraction modes. Before immersing the fiber, a rapid liquid-liquid extraction was performed using acetonitrile to remove the bulk of triglycerides. PDMS in the direct immersion mode showed the best performance. The method was fully validated obtaining a good linearity with a coefficient of correlation of over 0.9960 for all compounds, repeatability and accuracy values generally better than 10%, and very good limit of quantification values. © 2015 Elsevier B.V.
Disciplines :
Physical, chemical, mathematical & earth Sciences: Multidisciplinary, general & others
Author, co-author :
Barp, L.;  Scienze del Farmaco e Prodotti per la Salute Department, University of Messina, Viale Annunziata, Messina, 98168, Italy
Purcaro, Giorgia  ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes
Franchina, Flavio ;  Université de Liège - ULiège > Département de chimie (sciences) > Chimie analytique, organique et biologique
Zoccali, M.;  Scienze del Farmaco e Prodotti per la Salute Department, University of Messina, Viale Annunziata, Messina, 98168, Italy
Sciarrone, D.;  Scienze del Farmaco e Prodotti per la Salute Department, University of Messina, Viale Annunziata, Messina, 98168, Italy
Tranchida, P. Q.;  Scienze del Farmaco e Prodotti per la Salute Department, University of Messina, Viale Annunziata, Messina, 98168, Italy
Mondello, L.;  Scienze del Farmaco e Prodotti per la Salute Department, University of Messina, Viale Annunziata, Messina, 98168, Italy, Chromaleont S.r.l., C/o Scienze del Farmaco e Prodotti per la Salute Dept., University of Messina, Viale Annunziata, Messina, 98168, Italy, University Campus Bio-Medico of Rome, Via Álvaro del Portillo, 21, Rome, 00128, Italy
Language :
English
Title :
Determination of phthalate esters in vegetable oils using direct immersion solid-phase microextraction and fast gas chromatography coupled with triple quadrupole mass spectrometry
Publication date :
2015
Journal title :
Analytica Chimica Acta
ISSN :
0003-2670
eISSN :
1873-4324
Publisher :
Elsevier
Volume :
887
Pages :
237-244
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
MIUR - Ministero dell'Istruzione, dell'Università e della Ricerca [IT]
Available on ORBi :
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