The Immuno-Inflammatory Reaction in Crohn's Disease and Ulcerative Colitis: Characterisation, Genetics and Clinical Application. Focus on Tnf Alpha

Louis, Edouard

Article (Scientific journals)

Louis, Edouard

2001 • In Acta Gastro-Enterologica Belgica, 64 (1), p. 1-5

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https://hdl.handle.net/2268/22815

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11322060

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Abstract :

[en] Inflammatory bowel diseases are multifactorial polygenic diseases. The author has worked on the characterisation of the mucosal immuno-inflammatory reaction, on genetic predisposition and on potential clinical application of blood immuno-inflammatory markers in these diseases. This paper summarizes some aspects of this work, focusing on TNF. Following points are developed: production of TNF by inflamed mucosa, genetic control of TNF production, TNF gene polymorphim in inflammatory bowel disease, and evaluation of serum TNF as a marker of disease activity or evolutivity.

Disciplines :

Gastroenterology & hepatology

Author, co-author :

Louis, Edouard ; Université de Liège - ULiège > Département des sciences cliniques > Hépato-gastroentérologie

Language :

English

Title :

The Immuno-Inflammatory Reaction in Crohn's Disease and Ulcerative Colitis: Characterisation, Genetics and Clinical Application. Focus on Tnf Alpha

Publication date :

2001

Journal title :

Acta Gastro-Enterologica Belgica

ISSN :

0001-5644

eISSN :

1784-3227

Publisher :

Acta Medica Belgica, Bruxelles, Belgium

Volume :

Issue :

Pages :

1-5

Available on ORBi :

since 18 September 2009

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Bibliography

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