Seroprevalence of malignant catarrhal fever virus in captive wildebeest (Connochaetes sp.) in France.

[en] Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus carried asymptomatically by wildebeests (Connochaetes sp.) in sub-Saharan Africa. Although asymptomatic in wildebeest, AlHV-1 infection in a number of other ruminant species causes a severe and fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF). Several endangered species of captive ruminants are highly susceptible to developing WD-MCF if infected by AlHV-1, which is a critical concern in zoos, game reserves and wildlife parks where wildebeests are also kept in captivity. Here, we investigated the seroprevalence of AlHV-1 in 52 captive wildebeests randomly sampled from five different zoos in France. We found 46% (24/52) seropositive animals and detected AlHV-1 DNA in one of them, demonstrating that AlHV-1 infection is present in captive wildebeests in France. In an interesting manner, the repartition of seropositive wildebeests was not homogenous between zoos with 100% (20/20) of seronegative animals in three parks. These results further highlight the importance of considering WD-MCF as a threat for clinically susceptible species and encourage for testing AlHV-1 infection in captive wildebeests as a management control strategy.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Ortiz, Katia

Javaux, Justine ; Université de Liège - ULiège > Immunologie et vaccinologie

Simon, Marie

Petit, Thierry

Clavel, Sylvie

Lamglait, Benjamin

Blanc, Barbara

Brunet, Alice

Myster, Françoise ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Vaccinologie vétérinaire

Li, Hong

Dewals, Benjamin G ; Université de Liège - ULiège > Immunologie et vaccinologie

Language :

English

Title :

Seroprevalence of malignant catarrhal fever virus in captive wildebeest (Connochaetes sp.) in France.

Publication date :

2018

Journal title :

Transboundary and Emerging Diseases

ISSN :

1865-1674

eISSN :

1865-1682

Publisher :

Wiley, Berlin, Germany

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

Available on ORBi :

since 06 September 2018

Statistics

Number of views

55 (2 by ULiège)

Number of downloads

0 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Davison, A. J., Eberle, R., Ehlers, B., Hayward, G. S., McGeoch, D. J., Minson, A. C., & Thiry, E. (2009). The order Herpesvirales. Archives of Virology, 154(1), 171–177. https://doi.org/10.1007/s00705-008-0278-4[doi]
Decker, L. L., Klaman, L. D., & Thorley-Lawson, D. A. (1996). Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals. Journal of Virology, 70(5), 3286–3289.
Dewals, B., Boudry, C., Farnir, F., Drion, P. V., & Vanderplasschen, A. (2008). Malignant catarrhal fever induced by alcelaphine herpesvirus 1 is associated with proliferation of CD8 + T cells supporting a latent infection. PLoS ONE, 3(2), e1627. https://doi.org/10.1371/journal.pone.0001627
Dewals, B., Boudry, C., Gillet, L., Markine-Goriaynoff, N., de Leval, L., Haig, D. M., & Vanderplasschen, A. (2006). Cloning of the genome of Alcelaphine herpesvirus 1 as an infectious and pathogenic bacterial artificial chromosome. Journal of General Virology, 87(Pt 3), 509–517. https://doi.org/10.1099/vir.0.81465-0
Dewals, B. G., & Vanderplasschen, A. (2011). Malignant catarrhal fever induced by Alcelaphine herpesvirus 1 is characterized by an expansion of activated CD3 + CD8 + CD4- T cells expressing a cytotoxic phenotype in both lymphoid and non-lymphoid tissues. Veterinary Research, 42(1), 95. https://doi.org/10.1186/1297-9716-42-95
Ensser, A., Pflanz, R., & Fleckenstein, B. (1997). Primary structure of the alcelaphine herpesvirus 1 genome. Journal of Virology, 71(9), 6517–6525.
Flach, E. J., Reid, H., Pow, I., & Klemt, A. (2002). Gamma herpesvirus carrier status of captive artiodactyls. Research in Veterinary Science, 73(1), 93–99. https://doi.org/10.1016/s0034-5288(02)00094-2
Frontoso, R., Autorino, G. L., Friedrich, K. G., Li, H., Eleni, C., Cocumelli, C., & Scicluna, M. T. (2016). An acute multispecies episode of sheep-associated malignant catarrhal fever in captive wild animals in an Italian zoo. Transboundary and Emerging Diseases, 63(6), 621–627. https://doi.org/10.1111/tbed.12321
Haig, D. M., Grant, D., Deane, D., Campbell, I., Thomson, J., Jepson, C., & Russell, G. C. (2008). An immunisation strategy for the protection of cattle against alcelaphine herpesvirus-1-induced malignant catarrhal fever. Vaccine, 26(35), 4461–4468. https://doi.org/10.1016/j.vaccine.2008.06.056
Kumar, S., Stecher, G., & Tamura, K. (2016). MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. Molecular Biology and Evolution, 33(7), 1870–1874. https://doi.org/10.1093/molbev/msw054
Lankester, F., Lugelo, A., Mnyambwa, N., Ndabigaye, A., Keyyu, J., Kazwala, R., & Russell, G. C. (2015). Alcelaphine Herpesvirus-1 (Malignant Catarrhal Fever Virus) in Wildebeest Placenta: Genetic Variation of ORF50 and A9.5 Alleles. PLoS ONE, 10(5), e0124121. https://doi.org/10.1371/journal.pone.0124121
Lankester, F., Lugelo, A., Werling, D., Mnyambwa, N., Keyyu, J., Kazwala, R., & Haig, D. (2016). The efficacy of alcelaphine herpesvirus-1 (AlHV-1) immunization with the adjuvants Emulsigen(R) and the monomeric TLR5 ligand FliC in zebu cattle against AlHV-1 malignant catarrhal fever induced by experimental virus challenge. Veterinary Microbiology, 195, 144–153. https://doi.org/10.1016/j.vetmic.2016.09.019
Lankester, F., Russell, G. C., Lugelo, A., Ndabigaye, A., Mnyambwa, N., Keyyu, J., & Cleaveland, S. (2016). A field vaccine trial in Tanzania demonstrates partial protection against malignant catarrhal fever in cattle. Vaccine, 34(6), 831–838. https://doi.org/10.1016/j.vaccine.2015.12.009
Li, H., Cunha, C. W., Taus, N. S., & Knowles, D. P. (2014). Malignant catarrhal fever: Inching toward understanding. Annual Review of Animal Biosciences, 2, 209–233. https://doi.org/10.1146/annurev-animal-022513-114156
Li, H., Dyer, N., Keller, J., & Crawford, T. B. (2000). Newly recognized herpesvirus causing malignant catarrhal fever in white-tailed deer (Odocoileus virginianus). Journal of Clinical Microbiology, 38(4), 1313–1318.
Li, H., Gailbreath, K., Flach, E. J., Taus, N. S., Cooley, J., Keller, J., & Crawford, T. B. (2005). A novel subgroup of rhadinoviruses in ruminants. Journal of General Virology, 86(Pt 11), 3021–3026. https://doi.org/10.1099/vir.0.81238-0
Li, H., McGuire, T. C., Muller-Doblies, U. U., & Crawford, T. B. (2001). A simpler, more sensitive competitive inhibition enzyme-linked immunosorbent assay for detection of antibody to malignant catarrhal fever viruses. Journal of Veterinary Diagnostic Investigation, 13(4), 361–364. https://doi.org/10.1177/104063870101300417
Li, H., Shen, D. T., Knowles, D. P., Gorham, J. R., & Crawford, T. B. (1994). Competitive inhibition enzyme-linked immunosorbent assay for antibody in sheep and other ruminants to a conserved epitope of malignant catarrhal fever virus. Journal of Clinical Microbiology, 32(7), 1674–1679.
Li, H., Taus, N. S., Jones, C., Murphy, B., Evermann, J. F., & Crawford, T. B. (2006). A devastating outbreak of malignant catarrhal fever in a bison feedlot. Journal of Veterinary Diagnostic Investigation, 18(1), 119–123. https://doi.org/10.1177/104063870601800120
Palmeira, L., Sorel, O., Van Campe, W., Boudry, C., Roels, S., Myster, F., & Dewals, B. G. (2013). An essential role for gamma-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle. Proceedings of the National Academy of Sciences of the United States of America, 110(21), E1933–E1942. https://doi.org/10.1073/pnas.1216531110
Plowright, W. (1967). Malignant catarrhal fever in East Africa 3. Neutralizing antibody in free-living wildebeest. Research in Veterinary Science, 8(1), 129–136.
Plowright, W. (1990). Malignant catarrhal fever virus. In B. Morein & Z. Dinter (Ed.), Virus infections of ruminants (pp. 123–150). Amsterdam: Elsevier.
Pretorius, J. A., Oosthuizen, M. C., & van Vuuren, M. (2008). Gammaherpesvirus carrier status of black wildebeest (Connochaetes gnou) in South Africa. Journal of the South African Veterinary Association, 79(3), 136–141.
Reid, H. W. (2000). Malignant catarrhal fever Reviews of Infectious Diseases, 2(1), 20–22.
Reid, H. W., Buxton, D., McKelvey, W. A., Milne, J. A., & Appleyard, W. T. (1987). Malignant catarrhal fever in Pere David's deer. The Veterinary Record, 121(12), 276–277. https://doi.org/10.1136/vr.121.12.276
Russell, G. C., Stewart, J. P., & Haig, D. M. (2009). Malignant catarrhal fever: A review. The Veterinary Journal, 179(3), 324–335. https://doi.org/10.1016/j.tvjl.2007.11.007
Seal, B. S., Heuschele, W. P., & Klieforth, R. B. (1989). Prevalence of antibodies to alcelaphine herpesvirus-1 and nucleic acid hybridization analysis of viruses isolated from captive exotic ruminants. American Journal of Veterinary Research, 50(9), 1447–1453.
Tamura, K., & Nei, M. (1993). Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Molecular Biology and Evolution, 10(3), 512–526. https://doi.org/10.1093/oxfordjournals.molbev.a040023
Whitaker, K. A., Wessels, M. E., Campbell, I., & Russell, G. C. (2007). Outbreak of wildebeest-associated malignant catarrhal fever in Ankole cattle. The Veterinary Record, 161(20), 692–695. https://doi.org/10.1136/vr.161.20.692
Zhu, H., Huang, Q., Hu, X., Chu, W., Zhang, J., Jiang, L., & Cheng, S. (2018). Caprine herpesvirus 2-associated malignant catarrhal fever of captive sika deer (Cervus nippon) in an intensive management system. BMC Veterinary Research, 14(1), 38. https://doi.org/10.1186/s12917-018-1365-8