Seroprevalence of malignant catarrhal fever virus in captive wildebeest (Connochaetes sp.) in France.

[en] Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus carried asymptomatically by wildebeests (Connochaetes sp.) in sub-Saharan Africa. Although asymptomatic in wildebeest, AlHV-1 infection in a number of other ruminant species causes a severe and fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF). Several endangered species of captive ruminants are highly susceptible to developing WD-MCF if infected by AlHV-1, which is a critical concern in zoos, game reserves and wildlife parks where wildebeests are also kept in captivity. Here, we investigated the seroprevalence of AlHV-1 in 52 captive wildebeests randomly sampled from five different zoos in France. We found 46% (24/52) seropositive animals and detected AlHV-1 DNA in one of them, demonstrating that AlHV-1 infection is present in captive wildebeests in France. In an interesting manner, the repartition of seropositive wildebeests was not homogenous between zoos with 100% (20/20) of seronegative animals in three parks. These results further highlight the importance of considering WD-MCF as a threat for clinically susceptible species and encourage for testing AlHV-1 infection in captive wildebeests as a management control strategy.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Ortiz, Katia

Javaux, Justine ; Université de Liège - ULiège > Immunologie et vaccinologie

Simon, Marie

Petit, Thierry

Clavel, Sylvie

Lamglait, Benjamin

Blanc, Barbara

Brunet, Alice

Myster, Françoise ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Vaccinologie vétérinaire

Li, Hong

Dewals, Benjamin G ; Université de Liège - ULiège > Immunologie et vaccinologie

Language :

English

Title :

Seroprevalence of malignant catarrhal fever virus in captive wildebeest (Connochaetes sp.) in France.

Publication date :

2018

Journal title :

Transboundary and Emerging Diseases

ISSN :

1865-1674

eISSN :

1865-1682

Publisher :

Wiley, Berlin, Germany

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

Available on ORBi :

since 06 September 2018

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