Paper published in a journal (Scientific congresses and symposiums)
A comparison of the P300 and PET in patients with disorders of consciousness in absence of response to command
Annen, Jitka; Wolff, Audrey; Blandiaux, Séverine et al.
2018In European Journal of Neurology, 25 (S2)
Peer Reviewed verified by ORBi
 

Files


Full Text
2018-European_Journal_of_Neurology.pdf
Publisher postprint (8.92 MB)
ePresentations abstracts
Download
Full Text Parts
EAN_P3_PET.pdf
Author preprint (2.41 MB)
Presentation Slides
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
disorders of consciousness; P300; PET; minimally conscious state; unresponsive wakefulness syndrome
Abstract :
[en] Detection and interpretation of signs of "covert command following" in patients with disorders of consciousness (DOC) remains a challenge for clinicians. In this study, we used a tactile P3-based BCI in 12 patients without behavioral command following, attempting to establish "covert command following." These results were then confronted to cerebral metabolism preservation as measured with glucose PET (FDG-PET). One patient showed "covert command following" (i.e., above-threshold BCI performance) during the active tactile paradigm. This patient also showed a higher cerebral glucose metabolism within the language network (presumably required for command following) when compared with the other patients without "covert command-following" but having a cerebral glucose metabolism indicative of minimally conscious state. Our results suggest that the P3-based BCI might probe "covert command following" in patients without behavioral response to command and therefore could be a valuable addition in the clinical assessment of patients with DOC.
Research center :
Giga-consciousness
Disciplines :
Neurology
Author, co-author :
Annen, Jitka  ;  Université de Liège - ULiège > GIGA-CRC In vivo Imaging
Wolff, Audrey ;  Université de Liège - ULiège > GIGA : Coma Group
Blandiaux, Séverine ;  Université de Liège - ULiège > GIGA : Coma Group
Lejeune, Nicolas  
Chatelle, Camille ;  Université de Liège - ULiège > GIGA : Coma Group
Laureys, Steven  ;  Université de Liège - ULiège > GIGA : Coma Group
Language :
English
Title :
A comparison of the P300 and PET in patients with disorders of consciousness in absence of response to command
Publication date :
June 2018
Event name :
4th Congress of the European Academy of Neurology
Event place :
Lisbon, Portugal
Event date :
16 au 19 juin 2018
Audience :
International
Journal title :
European Journal of Neurology
ISSN :
1351-5101
eISSN :
1468-1331
Publisher :
Blackwell, Oxford, United Kingdom
Special issue title :
Abstracts of the 4th Congress of the European Academy of Neurology, Lisbon, Portugal, June 2018
Volume :
25
Issue :
S2
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 09 August 2018

Statistics


Number of views
215 (12 by ULiège)
Number of downloads
502 (1 by ULiège)

Bibliography


Similar publications



Contact ORBi