Reference : Contact allergy to benzalkonium chloride in patients using a steroid nasal spray: A r...
Scientific journals : Article
Human health sciences : Otolaryngology
http://hdl.handle.net/2268/226781
Contact allergy to benzalkonium chloride in patients using a steroid nasal spray: A report of 3 cases
English
Lechien, Jr [> >]
COSTA DE ARAUJO, Pedro [Centre Hospitalier Universitaire de Liège - CHU > Autres Services Médicaux > Service d'ORL, d'audiophonologie et de chir. cervico-faciale >]
De Marrez, LG [> >]
Halloy, JL, [> >]
Khalife, M [> >]
Saussez, S [> >]
Jan-2018
Ear, Nose, and Throat Journal
Medquest Communications
E20-E22
Yes (verified by ORBi)
International
0145-5613
OH
[en] Benzalkonium chloride (BAC) is a bactericidal preservative excipient commonly found in steroid nasal sprays used to treat allergic rhinitis and nasal polyposis. In rare cases, BAC can be responsible for type I and type IV hypersensitivity reactions that can manifest as rhinorrhea, which a clinician might misinterpret as a lack of response to nasal spray therapy rather than a complication of it. We report 3 cases of type IV hypersensitivity reactions in patients who were being treated with mometasone nasal spray. We describe the epidemiology, clinical features, diagnosis, and treatment of these reactions.
http://hdl.handle.net/2268/226781
https://www.ncbi.nlm.nih.gov/pubmed/29493726

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