magnetic resonance imaging; quantitative MRI; neuroscience
Abstract :
[en] Quantitative magnetic resonance (qMRI) finds increasing interest in neuroscience and clinical research due to its greater specificity and its sensitivity to microstructural properties of brain tissue - myelin, iron and water concentration. We introduce the hMRI toolbox, an easy-to-use open-source tool for data handling and processing of quantitative MRI data. This toolbox, embedded in the SPM framework, allows the estimation of quantitative MRI maps (longitudinal and transverse relaxation rates R1 and R2*, proton density PD, and magnetization transfer MT), followed by spatial registration in common space for statistical analysis. It also offers flexibility for calculation of novel MRI biomarkers of tissue microstructure. The hMRI toolbox can be downloaded from http://hmri.info.
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Author, co-author :
Balteau, Evelyne ; Université de Liège - ULiège > GIGA-CRC In vivo Imaging
Leutritz, Tobias; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Lutti, Antoine; LREN, DNC - CHUV, University Lausanne, Switzerland
Callaghan, Martina; University College London, United Kingdom
Draganski, Bogdan; LREN, DNC - CHUV, University Lausanne
Phillips, Christophe ; Université de Liège - ULiège > GIGA-CRC In vivo Imaging
Reimer, Enrico; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Ruthotto, Lars; Emory University, Atlanta, United States
Seif, Maryam; University of Zurich, Switzerland
Weiskopf, Nikolaus; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
