Abbasalizadeh S., Baharvand H. Technological progress and challenges towards cGMP manufacturing of human pluripotent stem cells based therapeutic products for allogeneic and autologous cell therapies. Biotechnol. Adv. 2013, 31:1600-1623.
Abbasalizadeh S., Larijani M.R., Samadian A., Baharvand H. Bioprocess development for mass production of size-controlled human pluripotent stem cell aggregates in stirred suspension bioreactor. Tissue Eng. Part C. Methods 2012, 18:831-851.
Aehle M., Bork K., Schaepe S., Kuprijanov A., Horstkorte R., Simutis R., Lübbert A. Increasing batch-to-batch reproducibility of CHO-cell cultures using a model predictive control approach. Cytotechnology 2012, 64:623-634.
Ashoori A., Moshiri B., Khaki-sedigh A., Reza M. Optimal control of a nonlinear fed-batch fermentation process using model predictive approach. J. Process Control 2009, 19:1162-1173.
Brandenberger R., Burger S., Campbell A., Fong T., Lapinskas E., Rowley J.A. Cell therapy bioprocessing. BioProcess Int. 2011, 9(S1):30-37.
Brown K.S., Hill C.C., Calero G.A., Myers C.R., Lee K.H., Sethna J.P., Cerione R.A. The statistical mechanics of complex signaling networks: nerve growth factor signaling. Phys. Biol. 2004, 1:184-195.
Burd T.L., Schembri C.T. Separation Chamber Located Radially Outward from Sample Chamber and Connected by Flow Restrictive Channel 1993, Google Patents.
Carlier A., Chai Y.C., Moesen M., Theys T., Schrooten J., Van Oosterwyck H., Geris L. Designing optimal calcium phosphate scaffold-cell combinations using an integrative model-based approach. Acta Biomater. 2011, 7:3573-3585.
Carrondo M.J.T., Alves P.M., Carinhas N., Glassey J., Hesse F., Merten O.W., Micheletti M., Noll T., Oliveira R., Reichl U., Staby A., Teixeira A.P., Weichert H., Mandenius C.F. How can measurement, monitoring, modeling and control Advance cell culture in industrial biotechnology?. Biotechnol. J. 2012, 7:1522-1529.
Causin P., Sacco R., Verri M. A multiscale approach in the computational modeling of the biophysical environment in artificial cartilage tissue regeneration. Biomech. Model Mechanobiol. 2013, 12:763-780.
Checa S., Prendergast P.J. Effect of cell seeding and mechanical loading on vascularization and tissue formation inside a scaffold: a mechano-biological model using a lattice approach to simulate cell activity. J. Biomech. 2010, 43:961-968.
Chen A.K.L., Reuveny S., Oh S.K.W. Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction. Biotechnol. Adv. 2013, 31:1032-1046.
Cierpka K., Elseberg C.L., Niss K., Kassem M., Salzig D., Czermak P. hMSC production in disposable bioreactors with regards to GMP and PAT. Chem. Ing. Tech. 2013, 85:67-75.
Csaszar E., Chen K., Caldwell J., Chan W., Zandstra P.W. Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures. Biotechnol. Bioeng. 2013, 111:1258-1264. 10.1002/bit.25163.
Csaszar E., Kirouac D.C., Yu M., Wang W.J., Qiao W.L., Cooke M.P., Boitano A.E., Ito C., Zandstra P.W. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell 2012, 10:218-229.
Demol J., Lambrechts D., Geris L., Schrooten J., Van Oosterwyck H. Towards a quantitative understanding of oxygen tension and cell density evolution in fibrin hydrogels. Biomaterials 2011, 32:107-118.
Diogo M.M., Da Silva C.L., Cabral J.M. Separation technologies for stem cell bioprocessing. Biotechnol. Bioeng. 2012, 109:2699-2709.
Dos Santos F., Andrade P.Z., Abecasis M.M., Gimble J.M., Chase L.G., Campbell A.M., Boucher S., Vemuri M.C., Da Silva C.L., Cabral J.M.S. Toward a clinical-grade expansion of mesenchymal stem cells from human sources: a microcarrier-based culture system under xeno-free conditions. Tissue Eng. Part C-Methods 2011, 17:1201-1210.
Dos Santos F.F., Andrade P.Z., Da Silva C.L., Cabral J.M.S. Bioreactor design for clinical-grade expansion of stem cells. Biotechnol. J. 2013, 8:644-654.
Fan Y., Hsiung M., Cheng C., Tzanakakis E.S. Facile engineering of xeno-free microcarriers for the scalable cultivation of human pluripotent stem cells in stirred suspension. Tissue Eng. Part A 2014, 20:588-599.
Fernandes T.G., Rodrigues C.A.V., Diogo M.M., Cabral J.M.S. Stem cell bioprocessing for regenerative medicine. J. Chem. Technol. Biotechnol. 2014, 89:34-47.
French A., Bure K., Brindley D.A. CASMI TSCC launch event, Paris, France, july 2013: an assessment of the key barriers to the commercialization and clinical adoption of pluripotent stem cell therapies. Rejuvenation Res. 2014, 17:84-88.
Frohlich M., Grayson W.L., Marolt D., Gimble J.M., Kregar-Velikonja N., Vunjak-Novakovic G. Bone grafts engineered from human adipose-derived stem cells in perfusion bioreactor culture. Tissue Eng. Part A 2010, 16:179-189.
Geris L., Reed A.A.C., Vander Sloten J., Simpson A.H.R.W., Van Oosterwyck H. Occurrence and treatment of bone atrophic non-unions investigated by an integrative approach. Plos Comput. Biol 2010, 6.
Goh T.K., Zhang Z.Y., Chen A.K., Reuveny S., Choolani M., Chan J.K., Oh S.K. Microcarrier culture for efficient expansion and osteogenic differentiation of human fetal mesenchymal stem cells. Biores. Open. Access 2013, 2:84-97.
Gonzalez-Gonzalez M., Rito-Palomares M. Aqueous two-phase systems strategies to establish novel bioprocesses for stem cells recovery. Crit. Rev. Biotechnol. Epub ahead of print 2013, 10.3109/07388551.2013.794125.
Gossett D.R., Weaver W.M., Mach A.J., Hur S.C., Tse H.T.K., Lee W., Amini H., Di Carlo D. Label-free cell separation and sorting in microfluidic systems. Anal. Bioanal. Chem. 2010, 397:3249-3267.
Grayson W.L., Frohlich M., Yeager K., Bhumiratana S., Chan M.E., Cannizzaro C., Wan L.Q., Liu X.S., Guo X.E., Vunjak-Novakovic G. Engineering anatomically shaped human bone grafts. Proc. Natl. Acad. Sci. USA 2010, 107:3299-3304.
Gutenkunst R.N., Waterfall J.J., Casey F.P., Brown K.S., Myers C.R., Sethna J.P. Universally sloppy parameter sensitivities in systems biology models. Plos Comput. Biol. 2007, 3:1871-1878.
Guyot Y., Papantoniou I., Chai Y.C., Van Bael S., Schrooten J., Geris L. A computational model for Cell/ECM growth on 3D surfaces using the level set method: a bone tissue engineering case study. Biomech. Model Mechanobiol. Epub ahead of print 2014, 10.1007/s10237-014-0577-5.
Hagenmuller H., Hitz M., Merkle H.P., Meinel L., Muller R. Design and validation of a novel bioreactor principle to combine online micro-computed tomography monitoring and mechanical loading in. Bone Tissue Eng. Rev. Sci. Instrum. 2010, 81:014303.
Hunt M.M., Meng G.L., Rancourt D.E., Gates I.D., Kallos M.S. Factorial experimental design for the culture of human embryonic stem cells as aggregates in stirred suspension bioreactors reveals the potential for interaction effects between bioprocess parameters. Tissue Eng. Part C-Methods 2014, 20:76-89.
Ingber D.E., Mow V.C., Butler D., Niklason L., Huard J., Mao J., Yannas I., Kaplan D., Vunjak-Novakovic G. Tissue engineering and developmental biology: going Biomimetic. Tissue Eng. 2006, 12:3265-3283.
Janes K.A., Kelly J.R., Gaudet S., Albeck J.G., Sorger P.K., Lauffenburger D.A. Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data. J. Comput. Biol. 2004, 11:544-561.
Janssen F.W., Van Dijkhuizen-Radersma R., Van Oorschot A., Oostra J., De Bruijn J.D., Van Blitterswijk C.A. Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study. J. Tissue Eng. Regen. Med. 2010, 4:12-24.
Jones M., Varella-Garcia M., Skokan M., Bryce S., Schowinsky J., Peters R., Vang B., Brecheisen M., Startz T., Frank N., Nankervis B. Genetic stability of bone marrow-derived human mesenchymal stromal cells in the quantum system. Cytotherapy 2013, 15:1323-1339.
Jukes J.M., Both S.K., Leusink A., Sterk L.M.T., Van Blitterswijk C.A., De Boer J. Endochondral bone tissue engineering using embryonic stem cells. Proc. Natl. Acad. Sci. USA 2008, 105:6840-6845.
Kerkhofs J., Roberts S., Luyten F., Van Oosterwyck H., Geris L. Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype. PLoS One 2012, 7. 10.1371/journal.pone.0034729.
Kim J., Ma T. Perfusion regulation of hMSC microenvironment and osteogenic differentiation in 3D scaffold. Biotechnol. Bioeng. 2012, 109:252-261.
Kinney M.A., Mcdevitt T.C. Emerging strategies for spatiotemporal control of stem cell fate and morphogenesis. Trends Biotechnol. 2013, 31:78-84.
Kirouac D.C., Zandstra P.W. The systematic production of cells for cell therapies. Cell Stem Cell 2008, 3:369-381.
Kirouac D.C., Madlambayan G.J., Yu M., Sykes E.A., Ito C., Zandstra P.W. Cell-cell interaction networks regulate blood stem and progenitor cell fate. Mol. Syst. Biol 2009, 5:293.
Lambrechts D., Roeffaers M., Kerckhofs G., Roberts S.J., Hofkens J., Van De Putte T., Van Oosterwyck H., Schrooten J. Fluorescent oxygen sensitive microbead incorporation for measuring oxygen tension in cell aggregates. Biomaterials 2013, 34:922-929.
Lambrechts T., Papantoniou I., Sonnaert M., Schrooten J., Aerts J.M. Model-based cell number quantification using online single-oxygen sensor data for tissue engineering perfusion bioreactors. Biotechnol. Bioeng 2014, 111:1982-1992. Epub ahead of print. http://dx.doi.org/10.1002/bit.25274.
Lenas P., Moos M., Luyten F.P. Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part I: from three-dimensional cell growth to biomimetics of in vivo development. Tissue Eng. Part B-Rev. 2009, 15:381-394.
Lim M., Shunjie C., Panoskaltsis N., Mantalaris A. Systematic experimental design for bioprocess characterization: elucidating transient effects of multi-cytokine contributions on erythroid differentiation. Biotechnol. Bioprocess Eng. 2012, 17:218-226.
Liu N., Zang R., Yang S.T., Li Y. Stem cell engineering in bioreactors for large-scale bioprocessing. Eng. Life Sci. 2013, 14:4-15.
Loring J.F., McDevitt T.C., Palecek S.P., Schaffer D.V., Zandstra P.W., Nerem R.M. A global assessment of stem cell engineering. Epub ahead of print 2014, Tissue Eng. Part A. 10.1089/ten.tea.2013.0468.
Marolt D., Campos I.M., Bhumiratana S., Koren A., Petridis P., Zhang G., Spitalnik P.F., Grayson W.L., Vunjak-Novakovic G. Engineering bone tissue from human embryonic stem cells. Proc. Natl. Acad. Sci. USA 2012, 109:8705-8709.
Martin I., Smith T., Wendt D. Bioreactor-based roadmap for the translation of tissue engineering strategies into clinical products. Trends Biotechnol. 2009, 27:495-502.
Mason C., Hoare M. Regenerative medicine bioprocessing: building a conceptual framework based on early studies. Tissue Eng. 2007, 13:301-311.
Mason C., Manzotti E. Regenerative medicine cell therapies: numbers of units manufactured and patients treated between 1988 and 2010. Regen. Med. 2010, 5:307-313.
Mason C., Mason J., Culme-Seymour E.J., Bonfiglio G.A., Reeve B.C. Cell therapy companies make Strong progress from October 2012 to March 2013 amid mixed stock market sentiment. Cell Stem Cell 2013, 12:644-647.
Matsuoka F., Takeuchi I., Agata H., Kagami H., Shiono H., Kiyota Y., Honda H., Kato R. Morphology-based prediction of osteogenic differentiation potential of human mesenchymal stem cells. Plos One 2013, 8. 10.1371/journal.pone.0055082.
Mercier S.M., Diepenbroek B., Wijffels R.H., Streefland M. Multivariate PAT solutions for biopharmaceutical cultivation: current progress and limitations. Trends Biotechnol 2014, 32:329-336.
Mentink A., Hulsman M., Groen N., Licht R., Dechering K.J., Van Der Stok J., Alves H.A., Dhert W.J., Van Someren E.P., Reinders M.J.T., Van Blitterswijk C.A., De Boer J. Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1. Biomaterials 2013, 34:4592-4601.
Nerem R. A global assessment of stem cell engineering. J. Tissue Eng. Regen. Med. 2012, 6:406.
Nienow A.W., Rafiq Q.A., Coopman K., Hewitt C.J. A potentially scalable method for the harvesting of hMSCs from microcarriers. Biochem. Eng. J 2014, 85:79-88.
Nold P., Brendel C., Neubauer A., Bein G., Hackstein H. Good manufacturing practice-compliant animal-free expansion of human bone marrow derived mesenchymal stroma cells in a closed hollow-fiber-based bioreactor. Biochem. Biophys. Res. Commun. 2013, 430:325-330.
Papantoniou I., Chai Y.C., Luyten F.P., Schrooten J. Process quality engineering for bioreactor-driven manufacturing of tissue engineered constructs for bone regeneration. Tissue Eng. Part C. Methods. 2012, 19:596-609.
Papantoniou I., Sonnaert M., Geris L., Luyten F.P., Schrooten J., Kerckhofs G. Three dimensional characterization of tissue-engineered constructs by contrast enhanced nanofocus computed tomography. Tissue Eng. Part C. Methods. 2013, 20:177-187.
Patti G.J., Yanes O., Siuzdak G. Metabolomics: the apogee of the omics trilogy. Nat. Rev. Mol. Cell Biol. 2012, 13:263-269.
Placzek M.R., Chung I.M., Macedo H.M., Ismail S., Blanco T.M., Lim M., Cha J.M., Fauzi I., Kang Y., Yeo D.C.L., Ma C.Y.J., Polak J.M., Panoskaltsis N., Mantalaris A. Stem cell bioprocessing: fundamentals and principles. J. R. Soc. Interface 2009, 6:209-232.
Ratcliffe E., Thomas R.J., Williams D.J. Current understanding and challenges in bioprocessing of stem cell-based therapies for regenerative medicine. Br. Med. Bull. 2011, 100:137-155.
Rathore A.S., Winkle H. Quality by design for biopharmaceuticals. Nat. Biotechnol. 2009, 27:26-34.
Roberts I., Baila S., Rice R.B., Janssens M.E., Nguyen K., Moens N., Ruban L., Hernandez D., Coffey P., Mason C. Scale-up of human embryonic stem cell culture using a hollow fibre bioreactor. Biotechnol. Lett. 2012, 34:2307-2315.
Roberts S.J., Geris L., Kerckhofs G., Desmet E., Schrooten J., Luyten F.P. The combined bone forming capacity of human periosteal derived cells and calcium phosphates. Biomaterials 2011, 32:4393-4405.
Roccio M., Schmitter D., Knobloch M., Okawa Y., Sage D., Lutolf M.P. Predicting stem cell fate changes by differential cell cycle progression patterns. Development 2013, 140:459-470.
Roelofs E., Engelsman M., Rasch C., Persoon L., Qamhiyeh S., De Ruysscher D., Verhaegen F., Pijls-Johannesma M., Lambin P., Consortium R. Results of a multicentric in silico clinical trial (ROCOCO) comparing radiotherapy with photons and protons for non-small cell lung cancer. J. Thorac. Oncol. 2012, 7:165-176.
Rojewski M.T., Fekete N., Baila S., Nguyen K., Furst D., Antwiler D., Dausend J., Kreja L., Ignatius A., Sensebe L., Schrezenmeier H. GMP-compliant isolation and expansion of bone marrow-derived MSCs in the closed, automated device quantum cell expansion system. Cell Transplant. 2013, 22:1981-2000.
Saeed A., Baharvand H. Biotechnol. Adv. 2013, 31:1600-1623.
Saito E., Liu Y.F., Migneco F., Hollister S.J. Strut size and surface area effects on long-term in vivo degradation in computer designed poly(L-lactic acid) three-dimensional porous scaffolds. Acta Biomater. 2012, 8:2568-2577.
Salter E., Goh B., Hung B., Hutton D., Ghone N., Grayson W.L. Bone tissue engineering bioreactors: a role in the clinic?. Tissue Eng. Part B Rev. 2012, 18:62-75.
Santoro R., Braissant O., Muller B., Wirz D., Daniels A.U., Martin I., Wendt D. Real-time measurements of human chondrocyte heat production during in vitro proliferation. Biotechnol. Bioeng. 2011, 108:3019-3024.
Santoro R., Krause C., Martin I., Wendt D. On-line monitoring of oxygen as a non-destructive method to quantify cells in engineered 3D tissue constructs. J. Tissue Eng. Regen. Med. 2012, 6:696-701.
Schop D., Janssen F.W., Van Rijn L.D.S., Fernandes H., Bloem R.M., De Bruijn J.D., Van Dijkhuizen-Radersma R. Growth, metabolism, and growth inhibitors of mesenchymal stem cells. Tissue Eng. Part A 2009, 15:1877-1886.
Scotti C., Piccinini E., Takizawa H., Todorov A., Bourgine P., Papadimitropoulos A., Barbero A., Manz M.G., Martin I. Engineering of a functional bone organ through endochondral ossification. Proc. Natl. Acad. Sci. USA 2013, 110:3997-4002.
Smeets B., Odenthal T., Tijskens E., Ramon H., Van Oosterwyck H. Quantifying the mechanical micro-environment during three-dimensional cell expansion on microbeads by means of individual cell-based modeling. Comp. Meth. Biomech. Biomed. Eng 2013, 16:1071-1084.
Smith Z.D., Nachman I., Regev A., Meissner A. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event. Nat. Biotechnol. 2010, 28:521-526.
Song M.J., Dean D., Tate M.L.K. Mechanical modulation of nascent stem cell lineage commitment in tissue engineering scaffolds. Biomaterials 2013, 34:5766-5775.
Spanholtz J., Preijers F., Tordoir M., Trilsbeek C., Paardekooper J., De Witte T., Schaap N., Dolstra H. Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process. Plos One 2011, 6.
Spencer T.J., Hidalgo-Bastida L.A., Cartmell S.H., Halliday I., Care C.M. In silico multi-scale model of transport and dynamic seeding in a bone tissue engineering perfusion bioreactor. Biotechnol. Bioeng. 2013, 110:1221-1230.
Tamura A., Kobayashi J., Yamato M., Okano T. Temperature-responsive poly(N-isopropylacrylamide)-grafted microcarriers for large-scale non-invasive harvest of anchorage-dependent cells. Biomaterials 2012, 33:3803-3812.
Teixeira A.P., Oliveira R., Alves P.M., Carrondo M.J.T. Advances in on-line monitoring and control of mammalian cell cultures: supporting the PAT initiative. Biotechnol. Adv. 2009, 27:726-732.
Timmins N.E., Kiel M., Gunther M., Heazlewood C., Doran M.R., Brooke G., Atkinson K. Closed system isolation and scalable expansion of human placental mesenchymal stem cells. Biotechnol. Bioeng. 2012, 109:1817-1826.
Volkmer E., Otto S., Polzer H., Saller M., Trappendreher D., Zagar D., Hamisch S., Ziegler G., Wilhelmi A., Mutschler W., Schieker M. Overcoming hypoxia in 3D culture systems for tissue engineering of bone in vitro using an automated, oxygen-triggered feedback loop. J. Mater. Sci. Mater. Med. 2012, 23:2793-2801.
Wallman L., Akesson E., Ceric D., Andersson P.H., Day K., Hovatta O., Falci S., Laurell T., Sundstrom E. Biogrid-a microfluidic device for large-scale enzyme-free dissociation of stem cell aggregates. Lab. Chip 2011, 11:3241-3248.
Wang Y., Cheng L., Gerecht S. Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013. Ann. Biomed. Eng. 2013, 42:1357-1372.
Wang Y., Chou B.K., Dowey S., He C.X., Gerecht S., Cheng L.Z. Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. Stem Cell Res. 2013, 11:1103-1116.
Ward A., Quinn K.P., Bellas E., Georgakoudi I., Kaplan D.L. Noninvasive metabolic imaging of engineered 3D human adipose tissue in a perfusion bioreactor. Plos One 2013, 8.
Warren V. Understanding regenerative medicine: a commissioner's viewpoint. Regen. Med 2013, 8(2):227-232.
Wendt D., Riboldi S.A., Cioffi M., Martin I. Bioreactors in tissue engineering: scientific challenges and clinical perspectives. Adv. Biochem. Eng. Biotechnol. 2009, 112:1-27.
Yeatts A.B., Both S.K., Yang W., Alghamdi H.S., Yang F., Fisher J.P., Jansen J.A. In vivo bone regeneration using tubular perfusion system bioreactor cultured nanofibrous scaffolds. Tissue Eng. Part A 2014, 20:139-146.
Yeatts A.B., Fisher J.P. Bone tissue engineering bioreactors: dynamic culture and the influence of shear stress. Bone 2011, 48:171-181.
Yeo D., Kiparissides A., Cha J.M., Aguilar-Gallardo C., Polak J.M., Tsiridis E., Pistikopoulos E.N., Mantalaris A. Improving embryonic stem cell expansion through the combination of perfusion and bioprocess model design. Plos One 2013, 8.
Zhou L., Kong J., Zhuang Y., Chu J., Zhang S., Guo M. Ex vivo expansion of bone marrow mesenchymal stem cells using microcarrier beads in a stirred bioreactor. Biotechnol. Bioprocess Eng. 2013, 18:173-184.
Zhou X.H., Holsbeeks I., Impens S., Sonnaert M., Bloemen V., Luyten F., Schrooten J. Noninvasive real-time monitoring by alamarblue (R) during in vitro culture of three-dimensional tissue-engineered bone constructs. Tissue Eng. Part C-Methods 2013, 19:720-729.
Zweigerdt R., Olmer R., Singh H., Haverich A., Martin U. Scalable expansion of human pluripotent stem cells in suspension culture. Nat. Protoc. 2011, 6:689-700.
Abbasalizadeh S., Baharvand H. Technological progress and challenges towards cGMP manufacturing of human pluripotent stem cells based therapeutic products for allogeneic and autologous cell therapies. Biotechnol. Adv. 2013, 31:1600-1623.
Chang T., Zimmerley M.S., Quinn K.P., Lamarre-Jouenne I., Kaplan D.L., Beaurepaire E., Georgakoudi I. Non-invasive monitoring of cell metabolism and lipid production in 3D engineered human adipose tissues using label-free multiphoton microscopy. Biomaterials 2013, 34:8607-8616.
Csaszar E., Kirouac D.C., Yu M., Wang W.J., Qiao W.L., Cooke M.P., Boitano A.E., Ito C., Zandstra P.W. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell 2012, 10:218-229.
Diogo M.M., da Silva C.L., Cabral J.M. Separation technologies for stem cell bioprocessing. Biotechnol. Bioeng. 2012, 109:2699-2709.
Hunt M.M., Meng G., Rancourt D.E., Gates I.D., Kallos M.S. Factorial experimental design for the culture of human embryonic stem cells as aggregates in stirred suspension bioreactors reveals the potential for interaction effects between bioprocess parameters. Tissue Eng. Part C Meth. 2014, 20:76-89.
Kinney M.A., McDevitt T.C. Emerging strategies for spatiotemporal control of stem cell fate and morphogenesis. Trends biotechnol. 2013, 31:78-84.
Lambrechts D., Roeffaers M., Kerckhofs G., Roberts S.J., Hofkens J., Van de Putte T., Van Oosterwyck H., Schrooten J. Fluorescent oxygen sensitive microbead incorporation for measuring oxygen tension in cell aggregates. Biomaterials 2013, 34:922-929.
Wu J., Tzanakakis S. Deconstructing stem cell population heterogeneity: single cell analysis and modeling approaches. Biotechnol. Adv. 2013, 31:1047-1062.
Yeo D., Kiparissides A., Cha J.M., Aguilar-Gallardo C., Polak J.M., Tsiridis E., Pistikopoulos E.N., Mantalaris A. Improving embryonic stem cell expansion through the combination of perfusion and bioprocess model design. PloS One 2013.
