Poster (Scientific congresses and symposiums)
VitriCell: the safest key for cryopreserving your valuable cells
Connan, Delphine; Ectors, Fabien; Vanderzwalmen, Pierre et al.
20166th edition science for business Biowin Day 2016
 

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Keywords :
VitriCell; cryopreservation; cells
Abstract :
[en] VITRICELL is a future spin-off company aiming at providing standard and customized solutions for safe and efficient cryopreservation of valuable and sensible eukaryotic cells. Developed in the Embryology unit of the Faculty of Veterinary Medicine of the University of Liège, the core methodology relies on aggregation of inventor’s pioneering expertises in the fields of stem cells engineering, vitrification of gametes and embryos and in assisted reproductive technologies. VITRICELL will soon provide researchers and clinicians with vitrification kits, allowing upgrade of the current yields and safety after cryopreservation of their high-value cells. The benefits of our method are the most prominent with fragile cell lines limited in expansion ability. VITRICELL’s current product is based on a novel and user-friendly, aseptic and automatable vitrification method in sealed french straws, with bio-safe and chemically defined media. The absence of any ice crystal formation avoids excessive cell dehydration and injuries to cell membranes. As a consequence, VITRICELL’s method results in a higher efficiency (recovery rates, morphology, pluripotency…) than conventional slow freezing for cryopreserving human pluripotent stem cells (hPSCs) and other sensitive stem cell-like lines and embryos from human and non-human species. VITRICELL’s future products developments focuses on (i) vitrification of higher cells numbers in larger containers, (ii) implementation of the method to current automation processes.
Research center :
FARAH - Fundamental and Applied Research for Animals and Health - ULiège
Giga-Development and Stem Cells - ULiège
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Biotechnology
Author, co-author :
Connan, Delphine;  VitriCell SA
Ectors, Fabien  ;  Université de Liège - ULiège > GIGA-Technology platforms : Plate-forme transgénique
Vanderzwalmen, Pierre ;  Université de Liège - ULiège > Doct. sc. vété. (Bologne)
Antoine, Nadine ;  Université de Liège - ULiège > Département de morphologie et pathologie (DMP) > Histologie
Grobet, Luc ;  Université de Liège - ULiège > Département de morphologie et pathologie (DMP) > Embryologie
Language :
English
Title :
VitriCell: the safest key for cryopreserving your valuable cells
Publication date :
08 December 2016
Number of pages :
A0
Event name :
6th edition science for business Biowin Day 2016
Event organizer :
Biowin
Event place :
Louvain-La-Neuve, Belgium
Event date :
8 décembre 2016
European Projects :
FP7 - 223410 - BEST-STEM CELLS - Biochemically Equivalent Substitutive Technology for Stem Cells
Name of the research project :
Vitricell: développement et valorisation de kits de vitrification de cellules en conditions aseptiques et chimiquement définies
Funders :
Service public de Wallonie : Direction générale opérationnelle de l'économie, de l'emploi et de la recherche - DG06
CE - Commission Européenne [BE]
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since 11 June 2018

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