Poster (Scientific congresses and symposiums)
Use of molecular dynamics simulations to study the interactions between barley allelochemicals and plant plasma membrane
Lebecque, Simon; Crowet, Jean-Marc; du Jardin, Patrick et al.
2018Applied bioinformatics in life sciences (2nd edition)
 

Files


Full Text
Poster_Leuven.pdf
Author preprint (1.84 MB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] Gramine and hordenine, two alkaloids produced by barley, were shown to inhibit the growth of a common weed (Matricaria recutita L.). This feature could be useful in order to reach a more sustainable weeds management. In vitro experiments have proven that both molecules do interact with lipid bilayers (made of a phosphatidylglycerol (PG) lipid) mimicking plant plasma membranes and are able to modify some of their properties. Moreover, gramine was shown to be more effective than hordenine in both inhibiting weeds growth and altering lipid bilayers properties, suggesting that interactions with membranes could be linked to their mode of action. Molecular dynamics (MD) simulations are carried out in order to get an insight into the molecular mechanisms that underlie these interactions with model membranes and to discriminate between gramine behavior and hordenine behavior.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Lebecque, Simon ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes
Crowet, Jean-Marc ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Laboratory of Molecular Biophysics at Interfaces
du Jardin, Patrick  ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Ingénierie des productions végétales et valorisation
Fauconnier, Marie-Laure  ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes
Delory, Benjamin;  Leuphana University > Institute of Ecology
Deleu, Magali  ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes
Lins, Laurence  ;  Université de Liège - ULiège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Chimie des agro-biosystèmes
Language :
English
Title :
Use of molecular dynamics simulations to study the interactions between barley allelochemicals and plant plasma membrane
Publication date :
March 2018
Event name :
Applied bioinformatics in life sciences (2nd edition)
Event date :
8 & 9 mars 2018
Audience :
International
Available on ORBi :
since 20 April 2018

Statistics


Number of views
134 (12 by ULiège)
Number of downloads
35 (8 by ULiège)

Bibliography


Similar publications



Contact ORBi