A simple clinical method for predicting the benefit of prone vs. supine positioning in reducing heart exposure during left breast radiotherapy

Kahan, Zsuzsanna; Rarosi, Ferenc; Gaal, Szilvia; Cserhati, Adrienn; Boda, Krisztina; Darazs, Barbara; Koszo, Renata; Lakosi, Ferenc; GULYBAN, Akos; COUCKE, Philippe; Varga, Zoltan

doi:10.1016/j.radonc.2017.12.021

Article (Scientific journals)

A simple clinical method for predicting the benefit of prone vs. supine positioning in reducing heart exposure during left breast radiotherapy

Kahan, Zsuzsanna; Rarosi, Ferenc; Gaal, Szilvia et al.

2018 • In Radiotherapy and Oncology

Peer Reviewed verified by ORBi

Permalink
https://hdl.handle.net/2268/221845

DOI
10.1016/j.radonc.2017.12.021

PubMed
29373194

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Keywords :

breast radiotherapy; Clinical tool; Heart protection; individual positioning; LAD protection

Abstract :

[en] Background and purpose: The benefit of reduced radiation heart exposure in the prone vs. supine position individually differs. In this prospective cohort study, the goal was to develop a simple method for the operation of a validated model for the prediction of preferable treatment position during left breast radiotherapy. Material and methods: In 100 cases, a single CT slice was utilized for the collection of the needed patientspecific data (in addition to body mass index, the distance of the LAD from the chest wall and the area of the heart included in the radiation fields at the middle of the heart in the supine position). Outcome was analyzed in relation to the full CT series acquired in both positions and dosimetric data. Results: Great consistency was found between the tested and original method regarding sensitivity and specificity. The prioritization of LAD dose, and the use of heart dose and position-specific dose constraints as safety measures ensure sensitivity and specificity values of 82.8% and 87.3%, respectively. In an additional ‘‘routine clinical practice” series of 60 patients the new method seemed feasible in routine clinical practice. External testing on a 28-case series indicated similar accuracy. Conclusion: We consider this simple clinical tool appropriate for assisting individual positioning aiming at maximum heart protection during left breast irradiation

Disciplines :

Oncology

Author, co-author :

Kahan, Zsuzsanna

Rarosi, Ferenc

Gaal, Szilvia

Cserhati, Adrienn

Boda, Krisztina

Darazs, Barbara

Koszo, Renata

Lakosi, Ferenc

GULYBAN, Akos ; Centre Hospitalier Universitaire de Liège - CHU > Service médical de radiothérapie

COUCKE, Philippe ; Centre Hospitalier Universitaire de Liège - CHU > Service médical de radiothérapie

Varga, Zoltan

Language :

English

Title :

A simple clinical method for predicting the benefit of prone vs. supine positioning in reducing heart exposure during left breast radiotherapy

Publication date :

January 2018

Journal title :

Radiotherapy and Oncology

ISSN :

0167-8140

eISSN :

1879-0887

Publisher :

Elsevier, Netherlands

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 05 April 2018

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