Rapid tests and transfusion safety in Niamey, Niger.

[en] To evaluate the virological safety of blood components provided by the Niamey blood transfusion center after undergoing rapid tests. Samples found negative with rapid tests (n = 222) were screened by the Abbott Prism assay. Positive samples were confirmed by appropriate methods. Of 222 samples, nine (4.1%) were reactive for all markers. After confirmation, seven samples were positive (i.e., 3.2% false-negative results) : five (2.3%) for the surface antigen of hepatitis B (HBsAg) and two (0.9%) for the antibody directed against the hepatitis C virus (HCV-Ab). No false negative results were observed for HIV-Ab (antibody directed against the Human Immunodeficiency Virus). The performance of the rapid tests used in Niamey to screen for transfusion-transmissible infections is not satisfactory, especially for hepatitis B and C. The use of more sensitive tests should be considered to minimize the risk of contaminating patients receiving blood components.

Disciplines :

Public health, health care sciences & services

Author, co-author :

Mayaki, Z.

Seydou, M.

Moutschen, Michel ; Université de Liège - ULiège > Département des sciences cliniques > GIGA-R:Immunopath. - Maladies infect. et médec. inter. gén.

Albert, Adelin ; Université de Liège - ULiège > Département des sciences de la santé publique > Département des sciences de la santé publique

Dardenne, Nadia ; Université de Liège - ULiège > Département des sciences de la santé publique > Biostatistique

Sondag, D.

Gossens, D.

Gérard, Catherine ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, humaines et path.

Language :

English

Title :

Rapid tests and transfusion safety in Niamey, Niger.

Alternative titles :

[en] Tests rapides et securite transfusionnelle a Niamey, Niger.

Publication date :

2017

Journal title :

Médecine et Santé Tropicales

ISSN :

2261-3684

eISSN :

2261-2211

Publisher :

John Libbey Eurotext, France

Volume :

Issue :

Pages :

95-100

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 30 March 2018

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