CDDO-Me amino acid conjugates and methods of use

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Patent (Patents)

Sporn, Michael B.; Liby, Karen T.; Cao, Martine et al.

2016

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https://hdl.handle.net/2268/221651

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Keywords :

CDDO; triterpenoid; antiinflammatory

Abstract :

[en] 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid amino acid derivatives having antiinflammatory properties are provided. Pharmaceutical compositions and methods for preventing ior treating inflammation or a disease or condition mediated by inflammation are described.

Disciplines :

Pharmacy, pharmacology & toxicology

Inventor :

Sporn, Michael B.; Dartmouth College > Pharmacology and Toxicology

Liby, Karen T.; Dartmouth College > Pharmacology and Toxicology

Cao, Martine ; Dartmouth College > Pharmacology and Toxicology

Onyango, Evans O.; Dartmouth College > Chemistry

Fu, Liangfeng; Dartmouth College > Chemistry

Gribble, Gordon W.; Dartmouth College > Chemistry

Language :

English

Title (54) :

CDDO-Me amino acid conjugates and methods of use

Publication date (43-45) :

22 March 2016

Filing date (22) :

11 February 2014

Patent/publication number (10-11) :

US9290455B2

Patent status (13) :

Priority number (30) :

14/177,569 US 11-02-2014

International classification (IPC) (51) :

A61K 31/21 (20060101); A61K 31/275 (20060101); A61K 31/40 (20060101); C07D 233/61 (20060101); C07C 235/84 (20060101); C07D 207/16 (20060101); C07D 209/08 (20060101)

European classification (ECLA) (52) :

C07D 233/61 (20130101); C07C 235/84 (20130101); C07J 63/008 (20130101); C07D 209/08 (20130101); C07D 207/16 (20130101)

Applicant (71) :

Trustees of Dartmouth College, Hanover, NH, US

Publication organism (19) :

United States Patent and Trademark Office

Available on ORBi :

since 28 March 2018

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