[en] A new amphiphilic poly(vinyl alcohol)-b-poly(acrylonitrile) (PVOH-b-PAN) copolymer obtained by selective hydrolysis of well-defined poly(vinyl acetate)-b-poly(acrylonitrile) copolymer synthesized by cobalt mediated radical polymerization was used for the preparation of PVOH-b-PAN based micelles with embedded silver nanoparticles. The successful formation of silver loaded micelles has been confirmed by UV–vis, DLS and TEM analysis and their antibacterial activity against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Pseudomonas aeruginosa (P. aeruginosa) and spore solution of Bacillus subtilis (B. subtilis) has been studied. PVOH-b-PAN based micelles with embedded silver nanoparticles showed a strong bactericidal effect against E. coli, S. aureus and P. aeruginosa and the minimum bactericidal concentration for each system (MBC) has been determined.
Research center :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Bryaskova, Rayna; University of Chemical Technology and Metallurgy, Sofia, Bulgaria > Department ‘‘Polymer Engineering”
Pencheva, Daniela; Bio-National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria
Kyulavska, Mariya; University of Chemical Technology and Metallurgy, Sofia, Bulgaria > Department ‘‘Polymer Engineering”
Bozukova, Dimitriya; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Debuigne, Antoine ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Detrembleur, Christophe ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Antibacterial activity of poly(vinyl alcohol)-b-poly(acrylonitrile) based micelles loaded with silver nanoparticles
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Spatz J.P., Mossmer S., and Moller M. Angew. Chem. Int. Ed. 35 (1996) 1510
Förster S., and Plantenberg T. Angew. Chem. Int. Ed. 41 (2002) 688-714
Hamley I.W. Nanotechnology 14 (2003) 39
Aqil A., Detrembleur Ch., Gilbert B., Jerome R., and Jerome C. Chem. Mater. 19 (2007) 2150
Lohmueller T., Bock E., and P Spatz J. Adv. Mater. 20 (2008) 2297
Sohn B.H., and Cohen R.E. Acta Polym. 47 (1996) 340
Antonietti M., Förster S., Hartmann J., and Oestreich S. Macromolecules 29 (1996) 3800
Cong Y., Fu J., Zhang Z., Cheng Z., Xing R., Li J., and Han Y. J. Appl. Polym. Sci. 100 (2006) 2737
Savarimuthu Ph.A. Mater. Lett. 63 (2009) 773
Lei Z., Zhang L., and Wei X. J. Colloid Interf. Sci. 324 (2008) 216
Voets I.K., de Keizer A., Frederik P.M., Jellema R., and Cohen Stuart M.A. J. Colloid Interf. Sci. 339 (2009) 317
Wang H., Wang X., Winnik M.A., and Manners I. J. Am. Chem. Soc. 130 (2008) 12921
Charlot A., Sciannamea V., Lenoir S., Faure E., Jerome R., Jerome Ch., Van De Weerdt C., Martial J., Archambeau C., Willet N., Duwez A.-S., Fustin Ch.-A., and Detrembleur Ch. J. Mater. Chem. 19 (2009) 4117
Debuigne A., Warnant J., Jérôme R., Voets I.K., Keizer A.d., Martien A., Stuart C., and Detrembleur Ch. Macromolecules 41 (2008) 2353
Bryaskova R., Willet N., Duwez A.-S., Debuigne A., Lepot L., Gilbert B., Jérôme Ch., Jérôme R., and Detrembleur Ch. Chem. - An Asian J. 4 (2009) 1338
Debuigne A., Poli R., Jerome Ch., Jerome R., and Detrembleur Ch. Progr. Polym. Sci. 34 (2009) 211
Debuigne A., Michaux C., Jérôme Ch., Jérôme R., Poli R., and Detrembleur Ch. Chem. - An Europ. J. 14 (2008) 7623
Huang Ch.-J., Lin J.-J., and Shieu F.-Sh. Jpn. J. Appl. Phys. 44 (2005) 6332
Liu H., Ge X., Ni Y., Ye Q., and Zhang Zh. Radiat. Phys. Chem. 61 (2001) 89
Baron S. Medical Microbiology. 4th ed. (1996), University of Texas Medical Branch, Galveston
Shrivastava S., Bera T., Roy A., Singh G., Ramachandrarao P., and Dash D. Nanotechnology 18 (2007) 225103
