[en] Herein, we developed a strainghtforward aqueous synthesis of unprecedented alternating peptide-peptoid copolymers via Ugi four-component reaction applied to dipeptides. Functional peptide-peptoid copolymers as well as block copolymers were produced in a single step in the presence of acrylic acid and carboxylic acid-terminated poly(ethylene glycol). The thermoresponsiveness of these polymers is highlighted
Research Center/Unit :
Center for Education and Research on Macromolecules (CERM) CESAM Complex and Entangled Systems from Atoms to Materials (CESAM)
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Al Samad, Assala ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
De Winter, Julien; University of Mons, Organic Synthesis and Mass Spectrometry Laboratory, Belgium
Gergaux, Pascal; University of Mons, Organic Synthesis and Mass Spectrometry Laboratory, Belgium
Jérôme, Christine ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Debuigne, Antoine ; University of Liège (ULiège), Complex and Entangled Systems from Atoms to Materials (CESAM), Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Unique alternating peptide-peptoid copolymers from dipeptides via Ugi reaction in water
Publication date :
21 November 2017
Journal title :
Chemical Communications
ISSN :
1359-7345
eISSN :
1364-548X
Publisher :
Royal Society of Chemistry, Cambridge, United Kingdom
Volume :
53
Issue :
90
Pages :
12240-12243
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique
