Article (Scientific journals)
Inhibiteur de la DPP-4 ou des SGLT2 apres echec de la metformine seule dans le diabete de type 2.
Paquot, Nicolas; Scheen, André
2017In Revue Médicale Suisse, 13 (571), p. 1410-1415
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Abstract :
[en] After failure of a monotherapy with metformin, dipeptidyl peptidase-4 inhibitors (gliptins) and sodium-glucose cotransporters type 2 (gliflozins) offer an alternative to the add-on of a sulphonylurea, especially in diabetic patients at risk of hypoglycaemia. The choice between a gliptin and a gliflozin may be guided by the individual patient characteristics : rather a gliptin in a patient without obesity or severe hyperglycaemia, in an elderly patient, with a frailty profile or with renal impairment; rather a gliflozin in an obese patient, with hypertension, hyperuricaemia, antecedents of cardiovascular disease (especially heart failure), without advanced renal insufficiency and with a low risk of urinary/genital infections or events linked to dehydration such as hypotension.
Disciplines :
Pharmacy, pharmacology & toxicology
Endocrinology, metabolism & nutrition
Author, co-author :
Paquot, Nicolas ;  Université de Liège > Département des sciences de la santé publique > Diabétologie, nutrition et maladies métaboliques
Scheen, André  ;  Université de Liège > Département des sciences cliniques > Département des sciences cliniques
Language :
French
Title :
Inhibiteur de la DPP-4 ou des SGLT2 apres echec de la metformine seule dans le diabete de type 2.
Alternative titles :
[en] DPP-4 or SGLT2 inhibitor added to metformin alone in type 2 diabetes
Publication date :
2017
Journal title :
Revue Médicale Suisse
ISSN :
1660-9379
Publisher :
Medecine et Hygiène, Switzerland
Special issue title :
Thérapeutique
Volume :
13
Issue :
571
Pages :
1410-1415
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 September 2017

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