Reference : Fast separation of triterpenoid saponins using supercritical fluid chromatography cou...
Scientific congresses and symposiums : Poster
Physical, chemical, mathematical & earth Sciences : Multidisciplinary, general & others
Fast separation of triterpenoid saponins using supercritical fluid chromatography coupled with single quadrupole mass spectrometry
Huang, Yang mailto [Université de Liège - ULiège > > > Doct. sc. bioméd. & pharma. (paysage)]
18th international symposium on advance in extraction technologies and 22th international symposium on separation sciences
[en] Triterpenoid saponins (TSs) are the most important components of some traditional Chinese medicines (TCMs) and have exhibited valuable pharmacological properties[1-2]. Supercritical fluid chromatography (SFC), considered as a green separation technique, is a potential alternative to LC for the analysis of TSs. However, the application of SFC-MS to the analysis of TSs has not yet been reported. In the present study, rapid and efficient SFC-MS methods were developed for the first time for the separation of both TSs standards (kudinosides and ginsenosides) and TSs from natural product extracts. Moreover, a comprehensive comparison between LC-MS and SFC-MS with respect to selectivity and running time was carried out using a mixture of TSs as test sample.
Researchers ; Professionals

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