[en] Capsaicin sensitive structures were found near the ventral surface of the medulla, at the exit of hypoglossal nerve roots in acute experiments on rats. Injection of 5-50 nl 0.01% capsaicin to the rostral region of the capsaicin-sensitive area was accompanied by the increase of arterial pressure and heart rate while injection to the caudal region provoked the decrease of these parameters. By the end of the 2nd week, rostral and caudal ventrolateral medulla showed asymmetric distribution of NADPH-d-positive cells, suggesting involvement of nitric oxide in the neurochemical rearrangements within the brainstem.
Koulchitsky, Stanislav ; Université de Liège > Département des sciences biomédicales et précliniques > Pharmacologie
Language :
English
Title :
Capsaicin-sensitive area in the ventral surface of the rat medulla
Defense date :
1996
Institution :
Institute of Physiology of the National Academy of Sciences of Belarus, Minsk, Belarus
Degree :
Master
Promotor :
Gourine, Valery
Commentary :
The results were partly published in the earlier article:
Koulchitsky, S.V., Azev O.A., Gourine A.V., Kulchitsky V.A. Capsaicin-sensitive area in the ventral surface of the rat medulla. Neurosci Lett, 1994. 182(2): p. 129-132
