Abstract :
[en] This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee
osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same
range than other pharmacological modalities used in this indication. Effectiveness of intraarticular
hyaluronic acid has also been highlighted based on ‘real-life’ data, together with the
clinical benefit of systematic repeated treatment cycles, and the influence of the molecular
weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful
to clinicians when making personalized care decisions.
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