Article (Scientific journals)
3D echocardiographic reference ranges for normal left ventricular volumes and strain: results from the EACVI NORRE study
BERNARD, Anne-Catherine; Addetia, K; DULGHERU, Raluca Elena et al.
2017In European Heart Journal. Cardiovascular Imaging
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Abstract :
[en] Aim: To obtain the normal ranges for 3D echocardiography (3DE) measurement of left ventricular (LV) volumes, function, and strain from a large group of healthy volunteers. Methods and results: A total of 440 (mean age: 45 ± 13 years) out of the 734 healthy subjects enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study had good-quality 3DE data sets that have been analysed with a vendor-independent software package allowing homogeneous measurements regardless of the echocardiographic machine used to acquire the data sets. Upper limits of LV end-diastolic and end-systolic volumes were larger in men (97 and 42 mL/m2) than in women (82 and 35 mL/m2; P < 0.0001). Conversely, lower limits of LV ejection fraction were higher in women than in men (51% vs. 50%; P < 0.01). Similarly, all strain components were higher in women than in men. Lower range was -18.6% in men and -19.5% in women for 3D longitudinal strain, -27.0% and -27.6% for 3D circumferential strain, -33.2% and -34.4% for 3D tangential strain and 38.8% and 40.7% for 3D radial strain, respectively. LV volumes decreased with age in both genders (P < 0.0001), whereas LV ejection fraction increased with age only in men. Among 3DE LV strain components, the only one, which did not change with age was longitudinal strain. Conclusion: The NORRE study provides applicable 3D echocardiographic reference ranges for LV function assessment. Our data highlight the importance of age- and gender-specific reference values for both LV volumes and strain.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
BERNARD, Anne-Catherine ;  Centre Hospitalier Universitaire de Liège - CHU > Service de cardiologie
Addetia, K
DULGHERU, Raluca Elena ;  Centre Hospitalier Universitaire de Liège - CHU > Service de cardiologie
Caballero, L
Sugimoto, T
Akhaladze, N
Athanassopoulos, George
Barone, D
Baroni, M
Cardim, Nuno
Hagendorff, Andreas
Hristova, K
Ilardi, Federica
Lopez, T
de la Morena, G
Popescu, Bogdan Alexandru
Penicka, M
Ozyigit, T
Carbonero J
van de Veire, N
von Bardeleben, R
Vinereanu, D
Zamorano J, L
Martinez, C
Magne, J
Cosyns, Bernard
Donal, Erwan
Habib, G
Badano, LP
Lang, RM
Lancellotti, Patrizio  ;  Université de Liège > Département des sciences cliniques > Imagerie cardiaque fonctionnelle par échographie
More authors (21 more) Less
Language :
English
Title :
3D echocardiographic reference ranges for normal left ventricular volumes and strain: results from the EACVI NORRE study
Publication date :
2017
Journal title :
European Heart Journal. Cardiovascular Imaging
ISSN :
2047-2404
eISSN :
2047-2412
Publisher :
Oxford University Press, Oxford, United Kingdom
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 23 June 2017

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