18-Fluoro-deoxyglucose uptake in inflammatory hepatic adenoma: A case report.

[en] Positron emission tomography computed tomography (PET-CT) using 18-Fluoro-deoxyglucose (18FDG) is an imaging modality that reflects cellular glucose metabolism. Most cancers show an uptake of 18FDG and benign tumors do not usually behave in such a way. The authors report herein the case of a 38-year-old female patient with a past medical history of cervical intraepithelial neoplasia and pheochromocytoma, in whom a liver lesion had been detected with PET-CT. The tumor was laparoscopically resected and the diagnosis of inflammatory hepatic adenoma was confirmed. This is the first description of an inflammatory hepatic adenoma with an 18FDG up-take.

Disciplines :

Gastroenterology & hepatology
Surgery

Author, co-author :

Liu, Willy

Delwaide, Jean ; Université de Liège > Département des sciences cliniques > Département des sciences cliniques

BLETARD, Noëlla ; Centre Hospitalier Universitaire de Liège - CHU > Service d'anatomie et cytologie pathologiques

Delvenne, Philippe ; Université de Liège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques

Meunier, Paul ; Université de Liège > Département des sciences cliniques > Département des sciences cliniques

Hustinx, Roland ; Université de Liège > Département des sciences cliniques > Médecine nucléaire

Detry, Olivier ; Université de Liège > Département des sciences cliniques > Département des sciences cliniques

Language :

English

Title :

18-Fluoro-deoxyglucose uptake in inflammatory hepatic adenoma: A case report.

Publication date :

April 2017

Journal title :

World Journal of Hepatology

eISSN :

1948-5182

Publisher :

Baishideng Publishing Group, China

Volume :

Issue :

Pages :

562-566

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 05 June 2017

Statistics

Number of views

102 (12 by ULiège)

Number of downloads

243 (6 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

See more details

publications

supporting

mentioning

contrasting

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Bibliography

Barthelmes L, Tait IS. Liver cell adenoma and liver cell adenomatosis. HPB (Oxford) 2005; 7: 186-196 (PMID: 18333188 DOI: 10.1080/13651820510028954)
Stoot JH, Coelen RJ, De Jong MC, Dejong CH. Malignant transformation of hepatocellular adenomas into hepatocellular carcinomas: a systematic review including more than 1600 adenoma cases. HPB (Oxford) 2010; 12: 509-522 (PMID: 20887318 DOI: 10.1111/j.1477-2574.2010.00222.x)
Vijay A, Elaffandi A, Khalaf H. Hepatocellular adenoma: An update. World J Hepatol 2015; 7: 2603-2609 (PMID: 26557953 DOI: 10.4254/wjh.v7.i25.2603)
Descottes B, Glineur D, Lachachi F, Valleix D, Paineau J, Hamy A, Morino M, Bismuth H, Castaing D, Savier E, Honore P, Detry O, Legrand M, Azagra JS, Goergen M, Ceuterick M, Marescaux J, Mutter D, de Hemptinne B, Troisi R, Weerts J, Dallemagne B, Jehaes C, Gelin M, Donckier V, Aerts R, Topal B, Bertrand C, Mansvelt B, Van Krunckelsven L, Herman D, Kint M, Totte E, Schockmel R, Gigot JF. Laparoscopic liver resection of benign liver tumors. Surg Endosc 2003; 17: 23-30 (PMID: 12364994)
Detry O, Govaerts L, Deroover A, Vandermeulen M, Meurisse N, Malenga S, Bletard N, Mbendi C, Lamproye A, Honoré P, Meunier P, Delwaide J, Hustinx R. Prognostic value of (18)F-FDG PET/CT in liver transplantation for hepatocarcinoma. World J Gastroenterol 2015; 21: 3049-3054 (PMID: 25780305 DOI: 10.3748/wjg.v21. i10.3049)
Hustinx R, Detry O. Hepatobiliary disease: primary and metastatic liver tumors. In: Cook G, Maisey M, Britton K, Chengazi V, editors. Clinical nuclear medicine. 4th ed. London, United Kingdom: Hodder Arnold, 2006: 661-672
Bioulac-Sage P, Balabaud C, Zucman-Rossi J. Subtype classification of hepatocellular adenoma. Dig Surg 2010; 27: 39-45 (PMID: 20357450 DOI: 10.1159/000268406)
Walther Z, Jain D. Molecular pathology of hepatic neoplasms: classification and clinical significance. Patholog Res Int 2011; 2011: 403929 (PMID: 21559202 DOI: 10.4061/2011/403929)
Patel PM, Alibazoglu H, Ali A, Fordham E, LaMonica G. 'Falsepositive' uptake of FDG in a hepatic adenoma. Clin Nucl Med 1997; 22: 490-491 (PMID: 9227877)
Sumiyoshi T, Moriguchi M, Kanemoto H, Asakura K, Sasaki K, Sugiura T, Mizuno T, Uesaka K. Liver-specific contrast agentenhanced magnetic resonance and 18F-fluorodeoxyglucose positron emission tomography findings of hepatocellular adenoma: report of a case. Surg Today 2012; 42: 200-204 (PMID: 22160355 DOI: 10.1007/s00595-011-0067-7)
Fosse P, Girault S, Hoareau J, Testard A, Couturier O, Morel O. Unusual uptake of 18FDG by a hepatic adenoma. Clin Nucl Med 2013; 38: 135-136 (PMID: 23334131 DOI: 10.1097/RLU.0b013e 318279b95a)
Sanli Y, Bakir B, Kuyumcu S, Ozkan ZG, Gulluoglu M, Bilge O, Turkmen C, Mudun A. Hepatic adenomatosis may mimic metastatic lesions of liver with 18F-FDG PET/CT. Clin Nucl Med 2012; 37: 697-698 (PMID: 22691518 DOI: 10.1097/RLU.0b013e 3182443ced)
Buc E, Dupre A, Golffier C, Chabrot P, Flamein R, Dubois A, Pezet D. Positive PET-CT scan in hepatocellular adenoma with concomitant benign liver tumors. Gastroenterol Clin Biol 2010; 34: 338-341 (PMID: 20227207 DOI: 10.1016/j.gcb.2010.01.018)
Nakashima T, Takayama Y, Nishie A, Asayama Y, Baba S, Yamashita Y, Shirabe K, Kubo Y, Hida T, Honda H. Hepatocellular adenoma showing high uptake of (18)F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2). Clin Imaging 2014; 38: 888-891 (PMID: 25034402 DOI: 10.1016/ j.clinimag.2014.06.005)
Magini G, Farsad M, Frigerio M, Serra C, Colecchia A, Jovine E, Vivarelli M, Feletti V, Golfieri R, Patti C, Fanti S, Franchi R, Lodi F, Boschi S, Bernardi M, Trevisani F. C-11 acetate does not enhance usefulness of F- 18 FDG PET/CT in differentiating between focal nodular hyperplasia and hepatic adenoma. Clin Nucl Med 2009; 34: 659-665 (PMID: 19893396 DOI: 10.1097/RLU.0b013e3181b53488)
Stephenson JA, Kapasi T, Al-Taan O, Dennison AR. Uptake of (18) FDG by a Hepatic Adenoma on Positron Emission Tomography. Case Reports Hepatol 2011; 2011: 276402 (PMID: 25954539 DOI: 10.1155/2011/276402)
Laurent-Bellue A, Girma A, Le Stanc E. Diagnostic challenge to characterise a liver hypermetabolic focus on fluorocholine (18F) PET/CT: a case report. Médecine Nucléaire 2013; 37: 282-288 (DOI: 10.1016/j.mednuc.2013.05.002)
Lim D, Lee SY, Lim KH, Chan CY. Hepatic adenoma mimicking a metastatic lesion on computed tomography-positron emission tomography scan. World J Gastroenterol 2013; 19: 4432-4436 (PMID: 23885159 DOI: 10.3748/wjg.v19.i27.4432)
Lee SY, Kingham TP, LaGratta MD, Jessurun J, Cherqui D, Jarnagin WR, Kluger MD. PET-avid hepatocellular adenomas: incidental findings associated with HNF1-a mutated lesions. HPB (Oxford) 2016; 18: 41-48 (PMID: 26776850 DOI: 10.1016/ j.hpb.2015.07.001)
Boellaard R, Delgado-Bolton R, Oyen WJ, Giammarile F, Tatsch K, Eschner W, Verzijlbergen FJ, Barrington SF, Pike LC, Weber WA, Stroobants S, Delbeke D, Donohoe KJ, Holbrook S, Graham MM, Testanera G, Hoekstra OS, Zijlstra J, Visser E, Hoekstra CJ, Pruim J, Willemsen A, Arends B, Kotzerke J, Bockisch A, Beyer T, Chiti A, Krause BJ. FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0. Eur J Nucl Med Mol Imaging 2015; 42: 328-354 (PMID: 25452219 DOI: 10.1007/s00259-014- 2961-x)
Son HB, Han CJ, Kim BI, Kim J, Jeong SH, Kim YC, Lee JO, Choi CY, Im SM. (Evaluation of various hepatic lesions with positron emission tomography). Taehan Kan Hakhoe Chi 2002; 8: 472-480 (PMID: 12506252)
Wang YT, Lu F, Zhu F, Qian ZB, Xu YP, Meng T. Primary hepatic tuberculoma appears similar to hepatic malignancy on F- 18 FDG PET/CT. Clin Nucl Med 2009; 34: 528-529 (PMID: 19617736 DOI: 10.1097/RLU.0b013e3181abb6f7)
Tan GJ, Berlangieri SU, Lee ST, Scott AM. FDG PET/CT in the liver: lesions mimicking malignancies. Abdom Imaging 2014; 39: 187-195 (PMID: 24233161 DOI: 10.1007/s00261-013-0043-3)
Kim YH, Kim JY, Jang SJ, Chung HW, Jang KS, Paik SS, Song SY, Choi YY. F- 18 FDG uptake in focal fatty infiltration of liver mimicking hepatic malignancy on PET/CT images. Clin Nucl Med 2011; 36: 1146-1148 (PMID: 22064098 DOI: 10.1097/ RLU.0b013e3182335f60)
McIntosh AL, Atshaves BP, Storey SM, Landrock KK, Landrock D, Martin GG, Kier AB, Schroeder F. Loss of liver FA binding protein significantly alters hepatocyte plasma membrane microdomains. J Lipid Res 2012; 53: 467-480 (PMID: 22223861 DOI: 10.1194/jlr.M019919)

Similar publications

Sorry the service is unavailable at the moment. Please try again later.