Article (Scientific journals)
Transversus abdominis plane block or intravenous lignocaine in open prostate surgery: a randomized controlled trial.
Maquoi, Isabelle; JORIS, Jean; Dresse, Caroline et al.
2016In Acta Anaesthesiologica Scandinavica, 60 (10), p. 1453-1460
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Abstract :
[en] BACKGROUND AND OBJECTIVES: Transversus abdominis plane block (TAP) and intravenous lignocaine are two analgesic techniques frequently used after abdominal surgery. We hypothesized that these two techniques improve post-operative analgesia after open prostate surgery and sought to compare their efficacy on immediate post-operative outcome after open prostate surgery. METHODS: After ethics committee approval, 101 patients were enrolled in this prospective study and randomly allocated to receive bilateral ultrasound-guided TAP (n = 34), intravenous lignocaine (n = 33) or placebo (n = 34). In addition, intravenous paracetamol was given every 6 h. The primary endpoint was the cumulative opioid consumption during the first 48 post-operative hours (median[IQR]). Secondary endpoints included pain scores at rest and upon coughing, need for rescue tramadol, incidence of post-operative nausea and vomiting (PONV), recovery of bowel function and incidence of bladder catheter-related discomfort. RESULTS: Cumulative piritramide consumption after 48 h was 28 [23] mg in the control group, 21 [29] mg in the TAP group and 21 [31] mg in the lignocaine group (P = 0.065). There was no significant difference in post-operative pain scores between groups. The proportions of patients requiring rescue tramadol, experiencing PONV or bladder catheter-related discomfort were similar in each group. Recovery of bowel function was also similar in the three groups. CONCLUSIONS: Our study suggests that TAP block and intravenous lignocaine do not improve the post-operative analgesia provided by systematic administration of paracetamol after open prostatectomy.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Maquoi, Isabelle 
JORIS, Jean ;  Centre Hospitalier Universitaire de Liège - CHU > Service d'anesthésie - réanimation
Dresse, Caroline 
VAN DEN BOSCH, Sabine ;  Centre Hospitalier Universitaire de Liège - CHU > Service d'anesthésie - réanimation
Venneman, I.
Brichant, Jean-François ;  Université de Liège > Département des sciences cliniques > Anesthésie et réanimation
HANS, Grégory ;  Centre Hospitalier Universitaire de Liège - CHU > Service d'anesthésie - réanimation
Language :
English
Title :
Transversus abdominis plane block or intravenous lignocaine in open prostate surgery: a randomized controlled trial.
Publication date :
2016
Journal title :
Acta Anaesthesiologica Scandinavica
ISSN :
0001-5172
eISSN :
1399-6576
Publisher :
Blackwell, Copenhagen, Denmark
Volume :
60
Issue :
10
Pages :
1453-1460
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
(c) 2016 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
Available on ORBi :
since 26 October 2016

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