Evaluation of a New Method for the Treatment of Invasive, Diffuse, and Unexcisable Lymphangiomas of the Oral Cavity with Defocus CO2 Laser Beam: A 20-Year Follow-Up
Namour, Samir; VAN HEUSDEN, Alain; Namour, Amauryet al.
2016 • In Photomedicine and Laser Surgery, 34 (2), p. 82-87
[en] Abstract
Objective: The aim of our study is to evaluate the efficiency of a new therapeutic method using CO2 laser to avoid
mutilation or total excision for the treatment of invasive, large and unexcisable oral lymphangiomas. Background
data: Cystic lymphatic malformations, or lymphangiomas, are mature lymphatic malformations, consisting of
abnormal lymphatic vessels. Surgical excision is considered by most surgeons to be the treatment of choice for
lymphangioma. Laser beam has been used to treat superficial or small lymphatic malformations by excision or by
photocoagulation, and to excise or photocoagulate small lymphangiomas. Patients and methods: Seventeen
patients with diffuse and unexcisable lymphangiomas were treated using a CO2 laser with specific settings: beam
was 2W in noncontact and defocus mode, power density was 0.63W/cm2 for irradiation time in the range of 3–
5min, and the estimated energy density range was 114.65–191.02 J/cm2. The beam diameter at the tissular impact
point was –2 cm. The laser beam was defocused to provoke a deep heat generation that would dry up the
lymphatic tissues and induce deep tissue necrosis that heals by fibrous tissue process. Results: The results were
satisfactory and stable, with localized recurrence in three cases. The recurrent areas were re-treated using the same
technique successfully and with no further recurrence. Conclusions: The use of CO2 laser under the suggested
irradiation conditions can be considered a useful technique for the treatment of invasive lymphangiomas.
Research Center/Unit :
d‐BRU - Dental Biomaterials Research Unit - ULiège
Disciplines :
Dentistry & oral medicine
Author, co-author :
Namour, Samir ; Université de Liège > Département de sciences dentaires > Département de sciences dentaires
VAN HEUSDEN, Alain ; Centre Hospitalier Universitaire de Liège - CHU > Institut de dentisterie - prothèse fixée
Namour, Amaury; Université de Liège - ULiège > Sciences dentaires
Zeinoun, Toni; Lebanese University > Department of oral and maxillo-facial surgery
Language :
English
Title :
Evaluation of a New Method for the Treatment of Invasive, Diffuse, and Unexcisable Lymphangiomas of the Oral Cavity with Defocus CO2 Laser Beam: A 20-Year Follow-Up
Publication date :
2016
Journal title :
Photomedicine and Laser Surgery
ISSN :
1549-5418
eISSN :
1557-8550
Publisher :
Mary Ann Liebert, Inc., Larchmont, United States - New York
Gloviczki, P., (2005) Vascular Malformations, , Philadelphia PA: Elsevier
(2012) Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, , 7th ed. New Jersey: Saunders Elsevier
Tulasi, N.R., John, A., Chauhan, I., Nagarajan, V., Geetha, G., Lymphangioma circumscriptum (2004) Int J Gynecol Cancer, 14, pp. 564-566
Gaddikeri, S., Vattoth, S., Gaddikeri, R.S., Congenital cystic neck masses: Embryology and imaging appearances, with clinicopathological correlation (2014) Curr Probl Diagn Radiol, 43, pp. 55-67
Boardman, S.J., Cochrane, L.A., Roebuck, D., Elliott, M.J., Hartley, B.E., Multimodality treatment of pediatric lymphatic malformations of the head and neck using surgery and sclerotherapy (2010) Arch Otolaryngol Head Neck Surg, 136, pp. 270-276
Zhou, Q., Zheng, J.W., Mai, H.M., Treatment guidelines of lymphatic malformations of the head and neck (2011) Oral Oncol, 47, pp. 1105-1109
Emran, M.A., Dubois, J., Laberge, L., Al-Jazaeri, A., Bü Tter, A., Yazbeck, S., Alcoholic solution of zein (Ethibloc) sclerotherapy for treatment of lymphangiomas in children (2006) J Pediatr Surg, 41, pp. 975-979
Zuckerman, D.A., Yeager, T.D., Percutaneous ethanol sclerotherapy (2007) Am J Radiol, 169, pp. 433-437
Erikçi, V., Hosxgör, M., Yildiz, M., Intralesional bleomycin sclerotherapy in childhood lymphangioma (2013) Turk J Pediatr, 55, pp. 396-400
Denton, A.S., Baker-Hines, R., Spittle, M.F., Radiotherapy is a useful treatment for lymphangioma circumscriptum: A report of two patients (1996) Clin Oncol, 8, pp. 400-401
Sasaki, R., Negishi, K., Akita, H., Suzuki, K., Matsunaga, K., Successful treatment of congenital lymphangioma circumscriptum of the vulva with CO2 and long-pulsed Nd:YAG lasers (2014) Case Rep Dermatol, 8 (6), pp. 1-4
Alani, H.M., Warren, R.M., Percutaneous photocoagulation of deep vascular lesions using a fiberoptic laser wand (1992) Ann Plast Surg, 29, pp. 143-148
Arslan, A., Gursoy, H., Cologlu, S., Treatment of lymphangioma with CO2 laser in the mandibular alveolar mucosa (2011) J Contemp Dent Pract, 12, pp. 493-496
McGill, T.J., Friedman, E.M., Healy, G.B., Laser surgery in the pediatric airway (1983) Otolaryngol Clin North Am, 16, pp. 865-870
Dixon, J.A., Davisrk Gilbertson, J.J., Laser photocoagulation of vascular malformations of the tongue (1986) Laryngoscope, 96, pp. 537-541
Suen, J.Y., Waner, M., Treatment of oral cavity vascular malformations using the neodymium:YAG laser (1989) Arch Otolaryngol Head Neck Surg, 115, pp. 1329-1333
White, B., Adkins, W.Y., The use of the carbon dioxide laser in head and neck lymphangioma (1986) Lasers Surg Med, 6, pp. 293-295
Gillis, T.M., Strong, M.S., Surgical lasers and soft tissue interactions (1983) Otolaryngol Clin North Am, 16, pp. 775-784
Polanyi, T.G., Laser physics (1983) Otolaryngol Clin North Am, 16, pp. 753-774
Balakrishnan, A., Baily, C.M., Lymphangioma of the tongue and use of surface photocoagulation laser (1991) J Laryngol Otol, 105, pp. 924-929
Cawson, R., Odell, E., (2008) Essentials of Oral Pathology and Oral Medicine, , 7th ed. London: Livingstone
Watanabe, M., Kishiyama, K., Ohkawara, A., Acquired progressive lymphangioma (1983) J Am Acad Dermatol, 8, pp. 663-667
Wierzbicka, E., Herbreteau, D., Robert, M., Lorette, G., Malformations lymphatiques kystiques (2006) Ann Dermatol Venereol, 133, pp. 597-601
Bitar, M.A., Emamian, S., Head and neck vascular and cystic lesions of infancy and early childhood: Challenges in diagnosis and management-update (2003) J Med Liban, 51, pp. 155-164
Park, Y.W., Kim, S.M., Min, B.G., Park, I.W., Lee, S.K., Lymphangioma involving the mandible: Immunohistochemical expressions for the lymphatic proliferation (2002) J Oral Pathol Med, 31, pp. 280-283
Yonetsu, K., Nakayama, E., Kawazu, T., Kanda, S., Ozeki, S., ShinoharaM.Value of contrast-enhancedmagnetic resonance imaging in differentiation of hemangiomas from lymphangiomas in the oral and maxillofacial region (1999) Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 88, pp. 496-500
Yonetsu, K., Nakayama, E., Miwa, K., Magnetic resonance imaging of oral and maxillofacial angiomas (1993) Oral Surg Oral Med Oral Pathol, 76, pp. 783-789
Brennan, T.D., Miller, A.S., Chen, S.Y., Lymphangiomas of the oral cavity: A clinicopathologic, immunohistochemical, and electron-microscopic study (1998) J Oral Maxillofac Surg, 55, pp. 932-935
Kukk, E., Lymboussaki, A., Taira, S., VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development (1996) Development, 122, pp. 3829-3837
Landthaler, M., Hohenleutner, U., Laser treatment of congenital vascular malformations (1990) Int Angiol, 9, pp. 208-213
Lille, S.T., Rand, R.P., Tapper, D., Gruss, J.S., The surgical management of giant cervicofacial lymphatic malformations (1996) J Pediatr Surg, 31, pp. 1648-1650
Emery, P.J., Bailey, C.M., Evans, J.N., Cystic hygroma of the head and neck. A review of 37 cases (1984) J Laryngol Otol, 98, pp. 613-619
Cohen, S.R., Thompson, J.W., Lymphangioma of the larynx in infants and children. A survey of pediatric lymphangioma (1986) Ann Otol Rhinol Laryngol Suppl, 127, pp. 1-20
Ravitch, M.M., Rush, B.F., Cystic hygroma (1986) Pediatric Surgery, pp. 533-539. , Chicago: year book medical publishers
Kennedy, T.L., Cystic hygroma-lymphangioma: A rare and still unclear entity (1989) Laryngoscope, 99, pp. 1-10
Landthaler, M., Haina, D., Waidelich, W., Braun-Falco, O.J., A three-year experience with the argon laser in dermatotherapy (1984) Dermatol Surg Oncol, 10, pp. 456-461
Shumaker, P.R., Dela Rosa, K.M., Krakowski, A., Treatment of lymphangioma circumscriptum using fractional carbon dioxide laser ablation (2013) Pediatr Dermatol, 30, pp. 584-586
Lanjouw, E., De Roos, K.P., Den Hollander, J.C., Prens, E.P., Acquired scrotal lymphangioma successfully treated using carbon dioxide laser ablation (2011) Dermatol Surg, 37, pp. 539-542
Angiero, F., Benedicenti, S., Benedicenti, A., Arcieri, K., Berne, E., Head and neck hemangiomas in pediatric patients treated with endolesional 980-nm diode laser (2009) Photomed Laser Surg, 27, pp. 553-559
Treharne, L.J., Murison, M.S., CO2 laser ablation of lymphangioma circumscriptum of the scrotum (2006) Lymphat Res Biol, 4, pp. 101-103
Huilgol, S.C., Neill, S., Barlow, R.J., CO2 laser therapy of vulval lymphangiectasia and lymphangioma circumscriptum (2002) Dermatol Surg, 28, pp. 575-577