[en] The objective of the present study was to evaluate the efficacy of a dry extract of Passiflora incarnata L. (Sedanxio®) in patients consulting for anxiety in general practice. A total of 2928 patients were included by 219 general practitioners. Patients were evaluated at baseline and 2 weeks later using the Hamilton Anxiety Scale. Results showed a very significant improvement in anxiety scores, from 25.6 (SD = 8.3) at baseline visit to 15.4 (SD = 7.7) at follow up visit (-41%) (p < 0.0001). The Hamilton psychic and somatic subscores improved similarly. In addition, 15.6% of the patients could be considered in remission at visit 2 (Hamilton Anxiety Scale less than 7). These results demonstrate the interest of Passiflora incarnata as a first line treatment of anxiety symptoms.
Disciplines :
Psychiatry
Author, co-author :
Ansseau, Marc ; Université de Liège > Département des sciences cliniques > Psychiatrie et psychologie médicale
SEIDEL, Laurence ; Centre Hospitalier Universitaire de Liège - CHU > Service d'Informations médico économiques (SIME)
CROSSET, A.
DIERCKXSENS, Y.
Albert, Adelin ; Université de Liège > Département des sciences de la santé publique > Département des sciences de la santé publique
Language :
English
Title :
A dry extract of passiflora incarnata L. (Sedanxio) as first intention treatment of patients consulting for anxiety problems in general practice.
Publication date :
2012
Journal title :
Acta Psychiatrica Belgica
ISSN :
0300-8967
Publisher :
Société Royale de Médecine Mentale de Belgique, Namur, Belgium
