[en] We describe a case of a 48-year-old woman who underwent a resection of a tectal pilocytic astrocytoma complicated by a sequence of fluctuating consciousness, psychosis with complex hallucinations and lasting sleeping disturbances in which she vividly acts out her dreams. Based on the clinical and anatomical evidence of this case, we propose the term locus coeruleus syndrome to describe this association of iatrogenic symptoms. Along with those of the locus coeruleus, lesions of the dorsal raphe nucleus, ventral tegmentum, substantia nigra pars compacta, the superior colliculus and other peduncular lesions (such as peduncular hallucinosis) are involved in the regulation of sleep-wake/arousal, behaviour, sleeping disorders and rapid eye movement atonia. However, iatrogenic lesion of the locus coeruleus could explain the complications on all levels in our patient.
Disciplines :
Genetics & genetic processes
Author, co-author :
Kronenburg, Annick
Spliet, Wim G.
Broekman, Marike
Robe, Pierre ; Université de Liège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Language :
English
Title :
Locus coeruleus syndrome as a complication of tectal surgery.
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Bibliography
Apuzzo M, Tung H. Supratentorial approaches to the pineal region. In: Apuzzo M, ed. Brain surgery: complication avoidance and management. New York: Churchill-Livingstone, 1993:486.
Benke T. Peduncular hallucinosis: a syndrome of impaired reality monitoring. J Neurol 2006;253:1561-71.
Berridge CW, Schmeichel BE, Espana RA. Noradrenergic modulation of wakefulness/ arousal. Sleep Med Rev 2012;16:187-97.
Berridge CW, Waterhouse BD. The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Brain Res Rev 2003;42:33-84.
Braun CM, Pivik RT. Effects of locus coeruleus lesions upon sleeping and waking in the rabbit. Brain Res 1981;230:133-51.
Bruce J, Stein B. Supracerebellar approaches in the pineal region. In: Apuzzo M, ed. Brain surgery: complication avoidance and management. New York: Churchill-Livingstone, 1993:511.
Jones BE, Harper ST, Halaris AE. Effects of locus coeruleus lesions upon cerebral monoamine content, sleep-wakefulness states and the response to amphetamine in the cat. Brain Res 1977;124:473-96.
Monti JM. The role of dorsal raphe nucleus serotonergic and non-serotonergic neurons, and of their receptors, in regulating waking and rapid eye movement (REM) sleep. Sleep Med Rev 2010;14:319-27.
Monti JM. The structure of the dorsal raphe nucleus and its relevance to the regulation of sleep and wakefulness. Sleep Med Rev 2010;14:307-17.
Roser F, Ritz R, Koerbel A, et al. Peduncular hallucinosis: Insights from a neurosurgical point of view. Neurosurgery 2005;57:E1068.
Monti JM, Monti D. The involvement of dopamine in the modulation of sleep and waking. Sleep Med Rev 2007;11:113-33.
van Dongen PA. The human locus coeruleus in neurology and psychiatry. (Parkinson's, Lewy body, Hallervorden-spatz, Alzheimer's and Korsakoff's disease, (pre)senile dementia, schizophrenia, affective disorders, psychosis). Prog Neurobiol 1981;17:97-139.
Waddell J, Heldt S, Falls WA. Posttraining lesion of the superior colliculus interferes with feature-negative discrimination of fear-potentiated startle. Behav Brain Res 2003;142:115-24.
Mahowald MW, Schenck CH. Rem sleep without atonia-from cats to humans. Arch Ital Biol 2004;142:469-78.
Yeh DD, Warnick RE, Ernst RJ. Management strategy for adult patients with dorsal midbrain gliomas. Neurosurgery 2002;50:735-8.
Similar publications
Sorry the service is unavailable at the moment. Please try again later.
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.