Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats

[en] Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide.

Disciplines :

Zoology

Author, co-author :

Goffard, Anne

Demanche, Christine

Arthur, Laurent

Pinçon, Claire

Michaux, Johan ; Université de Liège > Département des sciences de la vie > Génétique et physiologie des microalgues

Dubuisson, Jean

Language :

English

Title :

Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats

Publication date :

2015

Journal title :

Viruses

eISSN :

1999-4915

Publisher :

MDPI, Basel, Switzerland

Volume :

Pages :

6279–6290

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 06 January 2016

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