N. Anton, A. Jakhmola, and T.F. Vandamme Trojan microparticles for drug delivery Pharmaceutics 4 2012 1 25
F.J. Bayard, W. Thielemans, D.I. Pritchard, S.W. Paine, S.S. Young, P. Backman, P. Ewing, and C. Bosquillon Polyethylene glycol-drug ester conjugates for prolonged retention of small inhaled drugs in the lung J. Control. Release: Off. J. Control. Release Soc. 171 2013 234 240
M. Beck-Broichsitter, O.M. Merkel, and T. Kissel Controlled pulmonary drug and gene delivery using polymeric nano-carriers J. Control. Release: Off. J. Control. Release Soc. 161 2012 214 224
S. Belotti, A. Rossi, P. Colombo, R. Bettini, D. Rekkas, S. Politis, G. Colombo, A.G. Balducci, and F. Buttini Spray-dried amikacin sulphate powder for inhalation in cystic fibrosis patients: the role of ethanol in particle formation Eur. J. Pharm. Biopharm. Off. J. Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e. V 93 2015 165 172
M.E. Brewster, and T. Loftsson Cyclodextrins as pharmaceutical solubilizers Adv. Drug Deliv. Rev. 59 2007 645 666
F. Buttini, P. Colombo, A. Rossi, F. Sonvico, and G. Colombo Particles and powders: tools of innovation for non-invasive drug administration J. Control. Release 161 2012 693 702
A.H. Chow, H.H. Tong, P. Chattopadhyay, and B.Y. Shekunov Particle engineering for pulmonary drug delivery Pharm. Res. 24 2007 411 437
G. De Rosa, D. Larobina, M. Immacolata La Rotonda, P. Musto, F. Quaglia, and F. Ungaro How cyclodextrin incorporation affects the properties of protein-loaded PLGA-based microspheres: the case of insulin/hydroxypropyl-beta-cyclodextrin system J. Control. Release: Off. J. Control. Release Soc. 102 2005 71 83
H. Derendorf, R. Nave, A. Drollmann, F. Cerasoli, and W. Wurst Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma Eur. Respir. J. 28 2006 1042 1050
G. Dufour, B. Evrard, and P. de Tullio Rapid quantification of 2-hydroxypropyl-beta-cyclodextrin in liquid pharmaceutical formulations by 1H nuclear magnetic resonance spectroscopy Eur. J. Pharm. Sci.: Off. J. Eur. Fed. Pharm. Sci. 73 2015 20 28
B. Evrard, P. Bertholet, M. Gueders, M.-P. Flament, G. Piel, L. Delattre, A. Gayot, P. Leterme, J.-M. Foidart, and D. Cataldo Cyclodextrins as a potential carrier in drug nebulization J. Control. Release 96 2004 403 410
A.M. Healy, M.I. Amaro, K.J. Paluch, and L. Tajber Dry powders for oral inhalation free of lactose carrier particles Adv. Drug Deliv. Rev. 75 2014 32 52
S.T. Holgate, and R. Polosa The mechanisms, diagnosis, and management of severe asthma in adults Lancet 368 2006 780 793
M. Hoppentocht, P. Hagedoorn, H.W. Frijlink, and A.H. de Boer Technological and practical challenges of dry powder inhalers and formulations Adv. Drug Deliv. Rev. 75 2014 18 31
B.N. Lambrecht, and H. Hammad The immunology of asthma Nature Immunol. 16 2014 45 56
P. Lebrun, F. Krier, J. Mantanus, H. Grohganz, M. Yang, E. Rozet, B. Boulanger, B. Evrard, J. Rantanen, and P. Hubert Design space approach in the optimization of the spray-drying process Eur. J. Pharm. Biopharm.: Off. J. Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e. V 80 2012 226 234
T. Loftsson, and M.E. Brewster Pharmaceutical applications of cyclodextrins: basic science and product development J. Pharm. Pharmacol. 62 2010 1607 1621
T. Loftsson, S.B. Vogensen, M.E. Brewster, and F. Konradsdottir Effects of cyclodextrins on drug delivery through biological membranes J. Pharm. Sci. 96 2007 2532 2546
C. Loira-Pastoriza, J. Todoroff, and R. Vanbever Delivery strategies for sustained drug release in the lungs Adv. Drug Deliv. Rev. 75 2014 81 91
L. Matilainen, T. Toropainen, H. Vihola, J. Hirvonen, T. Jarvinen, P. Jarho, and K. Jarvinen In vitro toxicity and permeation of cyclodextrins in Calu-3 cells J. Control. Release: Off. J. Control. Release Soc. 126 2008 10 16
A. Minne, H. Boireau, M.J. Horta, and R. Vanbever Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients Eur. J. Pharm. Biopharm.: Off. J. Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 70 2008 839 844
L.B. Salem, C. Bosquillon, L.A. Dailey, L. Delattre, G.P. Martin, B. Evrard, and B. Forbes Sparing methylation of beta-cyclodextrin mitigates cytotoxicity and permeability induction in respiratory epithelial cell layers in vitro J. Control. Release: Off. J. Control. Release Soc. 136 2009 110 116
T. Higuchi, and K.A. Connors Phase solubility technique Adv. Anal. Chem. Instrum. 4 1965 117 212
F. Tewes, J. Brillault, W. Couet, and J.C. Olivier Formulation of rifampicin-cyclodextrin complexes for lung nebulization J. Control. Release: Off. J. Control. Release Soc. 129 2008 93 99
F. Tewes, K.J. Paluch, L. Tajber, K. Gulati, D. Kalantri, C. Ehrhardt, and A.M. Healy Steroid/mucokinetic hybrid nanoporous microparticles for pulmonary drug delivery Eur. J. Pharm. Biopharm.: Off. J. Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 85 2013 604 613
G.P. Thierry Van Hees, Sandrine Henry de Hassonville, Brigitte Evrard, and Luc Delattre Determination of the free/included piroxicam ratio in cyclodextrin complexes: comparison between UV spectrophotometry and differential scanning calorimetry Eur. J. Pharm. Sci.: Off. J. Eur. Fed. Pharm. Sci. 15 2002 347 353
F. Ungaro, R. d'Emmanuele di Villa Bianca, C. Giovino, A. Miro, R. Sorrentino, F. Quaglia, and M.I. La Rotonda Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: in vivo deposition and hypoglycaemic activity after delivery to rat lungs J. Control. Release: Off. J. Control. Release Soc. 135 2009 25 34
R. Vehring Pharmaceutical particle engineering via spray drying Pharm. Res. 25 2008 999 1022
R. Vehring, W.R. Foss, and D. Lechuga-Ballesteros Particle formation in spray drying J. Aerosol Sci. 38 2007 728 746
Y. Zhu, A. Chidekel, and T.H. Shaffer Cultured human airway epithelial cells (calu-3): a model of human respiratory function, structure, and inflammatory responses Crit. Care Res. Pract. 2010
