[en] Composite Crosslinked nanofibrous membranes of chitosan, ethylene glycol diglycidyl ether (EGDE) and polyethy- 10 lene oxide was successfully prepared with bead free morphology via electrospinning technique followed by heat mediated 11 chemical crosslinking. Architectural stability of nanofiber mat in aqueous medium was achieved by chemical crosslinking of 12 only 1% EGDE, and tensile strength tests revealed that increasing EGDE content has considerably enhance the elastic modu- 13 lus of nanofibers. The structure, morphology and mechanical properties of nanofibers were characterized by Attenuated Total 14 Reflection-Fourier Transform Infrared spectroscopy (ATR–FTIR), scanning electron microscopy (SEM) and Instron machine, 15 respectively. Skin fibroblasts and endothelial cells showedgood attachment, proliferation and viability on crosslinked electrospun 16 membranes. The results indicate a good biocompatibility and non-toxic nature of the resulted membrane.
Research center :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Aqil, Abdelhafid ; University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Tchemtchoua Tateu, Victor ; University of Liège (ULg), GIGA Research Center, Laboratory of Connective Tissues
Colige, Alain ; University of Liège (ULg), GIGA Research Center, Laboratory of Connective Tissues
Atanasova, Ganka; University of Namur (FUNDP), Laboratory of Cells and Tissues
Poumay, Yves; University of Namur (FUNDP), Laboratory of Cells and Tissues
Jérôme, Christine ; University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Preparation and characterizations of EGDE crosslinked chitosan electrospun membranes
Publication date :
2015
Journal title :
Clinical Hemorheology and Microcirculation
ISSN :
1386-0291
Publisher :
IOS Press, Amsterdam, Netherlands
Volume :
60
Issue :
1
Pages :
39-50
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
The Walloon Region (Directorate General for Technologies, Research, and Energy
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