[en] Bisphenol A (BPA) is documented in several studies to be a well-known source of food contamination. Recently, the European Union took a series of measures, including a ban for the import and sale of polycarbonate (PC) baby bottles to reduce BPA exposure of infants. Plastic alternatives to PC, which have massively appeared on the Belgian market, include polypropylene (PP), silicone, polyamide (PA) and polyethersulfone (PES). In a recent opinion (No. 8697, 11.03.2010), the Belgian Superior Health Council issued its concern regarding the alternatives to PC currently used. Furthermore, they asked to investigate the possible risks associated with the use of these alternatives. In this study, a screening towards the endocrine activity of chemicals migrating from PC alternatives, identified by the group of Simoneau, was performed by using different reporter gene assays. Furthermore, the genotoxic potential of these compounds was also assessed with the Vitotox assay, an indicator test for DNA damage. The aim of the screening was to select the substances that may present a risk for human health and thus require further characterization.
Research Center/Unit :
FARAH - Fundamental and Applied Research for Animals and Health - ULiège
Disciplines :
Food science
Author, co-author :
Simon, Coraline ; Université de Liège > Département de sciences des denrées alimentaires (DDA) > Analyse des denrées alimentaires
Onghena, M.
Covaci, A.
Van Hoeck, E.
Van Loco, J.
Elskens, M.
Vandermarken, T.
Van Langenhove, K.
Damaegdt, H
Vandermeiren, K.
Scippo, Marie-Louise ; Université de Liège > Département de sciences des denrées alimentaires (DDA) > Analyse des denrées alimentaires
Language :
English
Title :
In vitro study toward the endocrine activity and the genotoxic potential of migration products from plastic baby bottles
Publication date :
2014
Event name :
34th International Symposium on Halogenated Persistent Organic Pollutants
Event date :
August 31st – September 5th 2014
Audience :
International
Journal title :
Organohalogen Compounds
ISSN :
1026-4892
Publisher :
Federal Environmental Agency, Vienna, Austria
Volume :
76
Pages :
826-829
Peer reviewed :
Peer Reviewed verified by ORBi
Name of the research project :
ALTPOLYCARB
Funders :
FPS Health Federal Public Service Health, Food Chain Safety and Environment [BE]