Genome-wide next-generation DNA and RNA sequencing reveals a mutation that perturbs splicing of the phosphatidylinositol glycan anchor biosynthesis class H gene (PIGH) and causes arthrogryposis in Belgian Blue cattle
Arthrogryposis syndrome; PIGH gene; Splice site mutation; Glycophosphatidyl inositol deficiency; Belgian blue cattle breed
Research center :
Giga-Genetics - ULiège
Disciplines :
Genetics & genetic processes Veterinary medicine & animal health
Author, co-author :
Sartelet, Arnaud ✱; Université de Liège > Département des Animaux de Production > GIGA-R : Génomique animale
Li, Wanbo ✱; Université de Liège - ULiège > Département des Animaux de Production > GIGA-R : Génomique animale
Pailhoux, Eric; Institut Scientifique de Recherche Agronomique - INRA > UMR1198 > Biologie du Développement et Reproduction
Richard, Christophe; Institut Scientifique de Recherche Agronomique - INRA > UMR1198 > Biologie du Développement et Reproduction
Tamma, Nico ; Université de Liège > Département de productions animales > GIGA-R : Génomique animale
Karim, Latifa ; Université de Liège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
Fasquelle, Corinne ; Université de Liège > Département des sciences biomédicales et précliniques > GIGA-R : Génétique humaine
Druet, Tom ; Université de Liège > Département de productions animales > GIGA-R : Génomique animale
Coppieters, Wouter ; Université de Liège > Département de productions animales > GIGA-R : Génomique animale
Georges, Michel ; Université de Liège > Département de productions animales > GIGA-R : Génomique animale
Charlier, Carole ; Université de Liège > Département de productions animales > GIGA-R : Génomique animale
✱ These authors have contributed equally to this work.
Language :
English
Title :
Genome-wide next-generation DNA and RNA sequencing reveals a mutation that perturbs splicing of the phosphatidylinositol glycan anchor biosynthesis class H gene (PIGH) and causes arthrogryposis in Belgian Blue cattle
Publication date :
2015
Journal title :
BMC Genomics
eISSN :
1471-2164
Publisher :
BioMed Central
Volume :
16
Issue :
316
Peer reviewed :
Peer Reviewed verified by ORBi
Name of the research project :
Rilouke
Funders :
DGA - Région wallonne. Direction générale de l'Agriculture [BE]
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