Article (Scientific journals)
Chitosan-coated electrospun nanofibers with antibacterial activity
Croisier, Florence; Sibret, Pierre; Dupont-Gillain, Christine C. et al.
2015In Journal of Materials Chemistry B, 3 (17), p. 3508-2517
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Keywords :
chitosan; electrospinning; antibacterial polymer
Abstract :
[en] Charged nanofibers were prepared by electrospinning (ESP) poly(ε-caprolactone) with a copolymer bearing carboxylic acid functions. The presence of these functions allowed exposing some negative charges on the fiber surface, by dipping the fibers in a phosphate buffer. A layer of chitosan, a polycation in acidic medium, was then deposited on the nanofiber surface, thanks to electrostatic attraction. Fibers were characterized at each step of the process and the influence of the copolymer architecture on chitosan deposition was discussed. The antibacterial activity of the resulting fibers was finally assessed.
Research center :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Chemistry
Materials science & engineering
Author, co-author :
Croisier, Florence ;  University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Sibret, Pierre ;  University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Dupont-Gillain, Christine C.;  Université catholique de Louvain, Institute of Condensed Matter and Nanosciences – Bio & Soft Matter (IMCN/BSMA)
Genet, Michel J.;  Université catholique de Louvain, Institute of Condensed Matter and Nanosciences – Bio & Soft Matter (IMCN/BSMA)
Detrembleur, Christophe ;  University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Jérôme, Christine  ;  University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Chitosan-coated electrospun nanofibers with antibacterial activity
Publication date :
07 May 2015
Journal title :
Journal of Materials Chemistry B
ISSN :
2050-750X
eISSN :
2050-7518
Publisher :
Royal Society of Chemistry
Volume :
3
Issue :
17
Pages :
3508-2517
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture [BE]
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique
the Walloon Region in the frame of the GOCELL project
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since 25 March 2015

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