Un cas rare d’arthrite fébrile

We present the case report of a 28 year old male
presenting with recurrent fever episodes and arthralgia.
Based on the presence of an inflammatory syndrome, a hyper-
ferritinemia, a salmon-pink rash and recurrent fever episodes,
the diagnosis of an adult onset Still’s disease (AOSD) was
made. A treatment with corticosteroids was started. During
the following years, the corticosteroids could not be tapered.
Eventually, a treatment with anakinra, an interleukin 1 (IL-1)
receptor antagonist was started, allowing tapering of the corticosteroids. This case report supports the possible role of IL-1 in the pathogenesis of AOSD, possibly through the inflammasome.