Maladie de Still de l’adulte; MSA; Anakinra; Adult onset Still’s disease; AOSD; Inflammasome
Résumé :
[en] We present the case report of a 28 year old male
presenting with recurrent fever episodes and arthralgia.
Based on the presence of an inflammatory syndrome, a hyper-
ferritinemia, a salmon-pink rash and recurrent fever episodes,
the diagnosis of an adult onset Still’s disease (AOSD) was
made. A treatment with corticosteroids was started. During
the following years, the corticosteroids could not be tapered.
Eventually, a treatment with anakinra, an interleukin 1 (IL-1)
receptor antagonist was started, allowing tapering of the corticosteroids. This case report supports the possible role of IL-1 in the pathogenesis of AOSD, possibly through the inflammasome.
Disciplines :
Rhumatologie
Auteur, co-auteur :
RINKIN, Charline ; Centre Hospitalier Universitaire de Liège - CHU > Rhumatologie
VAN DURME, Caroline ; Centre Hospitalier Universitaire de Liège - CHU > Rhumatologie
FAUTREL, B.
Malaise, Michel ; Université de Liège - ULiège > Département des sciences cliniques > Rhumatologie
Langue du document :
Français
Titre :
Un cas rare d’arthrite fébrile
Titre traduit :
[en] A rare case of arthritis and fever
Date de publication/diffusion :
juillet 2013
Titre du périodique :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Maison d'édition :
Université de Liège. Revue Médicale de Liège, Liège, Belgique
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