Article (Scientific journals)
Specific and non-specific enzymes for furanosyl-containing conjugates: biosynthesis, metabolism, and chemo-enzymatic synthesis.
Chlubnova, Ilona; Legentil, Laurent; Dureau, Remy et al.
2012In Carbohydrate Research, 356, p. 44-61
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Keywords :
Bacterial Proteins/chemistry/metabolism; Biocatalysis; Carbohydrate Sequence; Fungal Proteins/chemistry/metabolism; Galactose/analogs & derivatives/chemistry/metabolism; Glycoconjugates/biosynthesis/chemical synthesis; Glycoside Hydrolases/chemistry/metabolism; Glycosyltransferases/chemistry/metabolism; Intramolecular Transferases/chemistry/metabolism; Lipase/chemistry/metabolism; Molecular Sequence Data; Monosaccharides/biosynthesis/chemical synthesis; Polysaccharides/biosynthesis/chemical synthesis; Uridine Diphosphate/analogs & derivatives/chemistry/metabolism
Abstract :
[en] There is no doubt now that the synthesis of compounds of varying complexity such as saccharides and derivatives thereof continuously grows with enzymatic methods. This review focuses on recent basic knowledge on enzymes specifically involved in the biosynthesis and degradation of furanosyl-containing polysaccharides and conjugates. Moreover, and when possible, biocatalyzed approaches, alternative to standard synthesis, will be detailed in order to strengthen the high potential of these biocatalysts to go further with the preparation of rare furanosides. Interesting results will be also proposed with chemo-enzymatic processes based on nonfuranosyl-specific enzymes.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Chlubnova, Ilona ;  Université de Liège - ULiège > GIGA-R : Virologie - Immunologie
Legentil, Laurent
Dureau, Remy
Pennec, Alize
Almendros, Melanie
Daniellou, Richard
Nugier-Chauvin, Caroline
Ferrieres, Vincent
Language :
English
Title :
Specific and non-specific enzymes for furanosyl-containing conjugates: biosynthesis, metabolism, and chemo-enzymatic synthesis.
Publication date :
2012
Journal title :
Carbohydrate Research
ISSN :
0008-6215
eISSN :
1873-426X
Publisher :
Elsevier, United Kingdom
Volume :
356
Pages :
44-61
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2012 Elsevier Ltd. All rights reserved.
Available on ORBi :
since 11 March 2015

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