V. Abram, B. Berlec, A. Ota, M. Šentjurc, P. Blatnik, and N.P. Ulrih Effect of flavonoid structure on the fluidity of model lipid membranes Food Chem. 139 2013 804 813
J.M. Barichello, S. Kizuki, T. Tagami, L.A. Soares, T. Ishida, H. Kikuchi, and H. Kiwada Agitation during lipoplex formation harmonizes the interaction of siRNA to cationic liposomes Int. J. Pharm. 430 2012 359 365
F. Bigucci, A. Angela, B. Vitali, B. Saladini, T. Cerchiara, M.C. Gallucci, and B. Luppi Vaginal inserts based on chitosan and carboxymethylcellulose complexes for local delivery of chlorhexidine: preparation, characterization and antimicrobial activity Int. J. Pharm. 487 2015 456 463
F.X. Bosch, T.R. Broker, D. Forman, A.-B. Moscicki, M.L. Gillison, J. Doorbar, P.L. Stern, M. Stanley, M. Arbyn, M. Poljak, J. Cuzick, P.E. Castle, J.T. Schiller, L.E. Markowitz, W.A. Fisher, K. Canfell, L.A. Denny, E.L. Franco, M. Steben, M.A. Kane, M. Schiffman, C.J.L.M. Meijer, R. Sankaranarayanan, X. Castellsagué, J.J. Kim, M. Brotons, L. Alemany, G. Albero, M. Diaz, and S.D. Sanjosé Comprehensive control of human papillomavirus infections and related diseases Vaccine 31 2013 1 31
J.H. Caberg, P.M. Hubert, D.Y. Begon, M.F. Herfs, P.J. Roncarati, J.J. Boniver, and P.O. Delvenne Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes Carcinogenesis 29 2008 1441 1447
J.T. Chang, T.F. Kuo, Y.J. Chen, C.C. Chiu, Y.C. Lu, H.F. Li, C.R. Shen, and A.J. Cheng Highly potent and specific siRNAs against E6 or E7 genes of HPV16- or HPV18-infected cervical cancers Cancer Gene Ther. 17 2010 827 836
Y. Cu, and W.M. Saltzman Drug delivery: stealth particles give mucus the slip Nat. Mater. 8 2009 11 13
J. das Neves, M. Amiji, and B. Sarmento Mucoadhesive nanosystems for vaginal microbicide development: friend or foe? Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 3 2011 389 399
J. Doorbar Molecular biology of human papillomavirus infection and cervical cancer Clin. Sci. (Lond.) 110 2006 525 541
J. Doorbar, W. Quint, L. Banks, I.G. Bravo, M. Stoler, T.R. Broker, and M.A. Stanley The biology and life-cycle of human papillomaviruses Vaccine 30 2012 F55 70
K.L. Douglas, C.A. Piccirillo, and M. Tabrizian Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors Eur. J. Pharm. Biopharm. 68 2008 676 687
L.M. Ensign, R. Cone, and J. Hanes Nanoparticle-based drug delivery to the vagina: a review J. Control. Release 190 2014 500 514
A.C. Groo, and F. Lagarce Mucus models to evaluate nanomedicines for diffusion Drug Discov. Today 19 2014 1097 1108
J. Haedicke, and T. Iftner Human papillomaviruses and cancer Radiother. Oncol. 108 2013 397 402
M. Herfs, Y. Yamamoto, A. Laury, X. Wang, M.R. Nucci, M.E. McLaughlin-Drubin, K. Munger, S. Feldman, F.D. McKeon, W. Xian, and C.P. Crum A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer Proc. Natl. Acad. Sci. U. S. A. 109 2012 10516 10521
M. Kapoor, D.J. Burgess, and S.D. Patil Physicochemical characterization techniques for lipid based delivery systems for siRNA Int. J. Pharm. 427 2012 35 57
H.K. Kim, E. Davaa, C.S. Myung, and J.S. Park Enhanced siRNA delivery using cationic liposomes with new polyarginine-conjugated PEG-lipid Int. J. Pharm. 392 2010 141 147
I. Koltover, T. Salditt, J.O. Rädler, and C.R. Safinya An inverted hexagonal phase of cationic liposome-DNA complexes related to dna release and delivery Science 281 1998 78 81
A.K. Kundu, P.K. Chandra, S. Hazari, Y.V. Pramar, S. Dash, and T.K. Mandal Development and optimization of nanosomal formulations for siRNA delivery to the liver Eur. J. Pharm. Biopharm. 80 2012 257 267
S.K. Lai, Y.Y. Wang, and J. Hanes Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues Adv. Drug Deliv. Rev. 61 2009 158 171
C.L. Li, J.X. Cui, C.X. Wang, L. Zhang, Y.H. Li, L. Zhang, X. Xiu, Y.F. Li, and N. Wei Development of pegylated liposomal vinorelbine formulation using post-insertion technology Int. J. Pharm. 391 2010 230 236
K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method Methods 25 2001 402 408
OMS, 2013. Dernières statistiques mondiales sur le cancer en augmentation à 14,1 millions de nouveaux cas en 2012: L'augmentation marquée du cancer du sein demande des réponses IARC (OMS), Lyon France, pp. 1-3.
L.N. Putral, M.J. Bywater, W. Gu, N.A. Saunders, B.G. Gabrielli, G.R. Leggatt, and N.A. McMillan RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin Mol. Pharmacol. 68 2005 1311 1319
R.B.S. Roden, M. Ling, and T.C. Wu Vaccination to prevent and treat cervical cancer Hum. Pathol. 35 2004 971 982
F. Shi, L. Wasungu, A. Nomden, M.C.A. Stuart, E. Polushkin, J.B.F.N. Engbertsand, and D. Hoekstra Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions Biochem. J. 366 2002 333 341
J. Smisterova, A. Wagenaar, M.C. Stuart, E. Polushkin, G. ten Brinke, R. Hulst, J.B. Engberts, and D. Hoekstra Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery J. Biol. Chem. 276 2001 47615 47622
P.L. Stern, S.H. van der Burg, I.N. Hampson, T.R. Broker, A. Fiander, C.J. Lacey, H.C. Kitchener, and M.H. Einstein Therapy of human papillomavirus-related disease Vaccine 30 2012 F71 82
T. Tagami, K. Nakamura, T. Shimizu, T. Ishida, and H. Kiwada Effect of siRNA in PEG-coated siRNA-lipoplex on anti-PEG IgM production J. Control. Release 137 2009 234 240
T. Tagami, T. Suzuki, M. Matsunaga, K. Nakamura, N. Moriyoshi, T. Ishida, and H. Kiwada Anti-angiogenic therapy via cationic liposome-mediated systemic siRNA delivery Int. J. Pharm. 422 2012 280 289
B.C. Tang, M. Dawson, S.K. Lai, Y.Y. Wang, J.S. Suk, M. Yang, P. Zeitlin, M.P. Boyle, J. Fu, and J. Hanes Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier Proc. Natl. Acad. Sci. U. S. A. 106 2009 19268 19273
P. Vader, B.J. Crielaard, S.M. van Dommelen, R. van der Meel, G. Storm, and R.M. Schiffelers Targeted delivery of small interfering RNA to angiogenic endothelial cells with liposome-polycation-DNA particles J. Control. Release 160 2012 211 216
Z. Vanic, and N. Skalko-Basnet Nanopharmaceuticals for improved topical vaginal therapy: can they deliver? Eur. J. Pharm. Sci. 50 2013 29 41
M. Videira, A. Arranja, D. Rafael, and R. Gaspar Preclinical development of siRNA therapeutics: towards the match between fundamental science and engineered systems Nanomed. NBM 10 2013 689 702
S.Y. Wu, H.-I. Chang, M. Burgess, and N.A.J. McMillan Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system J. Control. Release 155 2011 418 426
S.Y. Wu, A. Singhania, M. Burgess, L.N. Putral, C. Kirkpatrick, N.M. Davies, and N.A. McMillan Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse models Gene Ther. 18 2011 14 22
M. Wytrwal, C. Leduc, M. Sarna, C. Goncalves, M. Kepczynski, P. Midoux, M. Nowakowska, and C. Pichon Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivatives Int. J. Pharm. 478 2014 372 382
S. Yang, Y. Chen, R. Ahmadie, and E.A. Ho Advancements in the field of intravaginal siRNA delivery J. Control. Release 167 2013 29 39
