Progenitor genealogy in the developing cerebral cortex

[en] The mammalian cerebral cortex is characterized by a complex histological organization that reflects the spatio-temporal stratifications of related stem and neural progenitor cells, which are responsible for the generation of distinct glial and neuronal subtypes during development. Some work has been done to shed light on the existing filiations between these progenitors as well as their respective contribution to cortical neurogenesis. The aim of the present review is to summarize the current views of progenitor hierarchy and relationship in the developing cortex and to further discuss future research directions that would help us to understand the molecular and cellular regulating mechanisms involved in cerebral corticogenesis.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Laguesse, Sophie ; Université de Liège - ULiège > Giga neurosciences

Peyre, Elise ; Université de Liège - ULiège > Giga - Neurosciences

Nguyen, Laurent ; Université de Liège - ULiège > GIGA - Neurosciences

Language :

English

Title :

Progenitor genealogy in the developing cerebral cortex

Publication date :

21 August 2014

Journal title :

Cell and Tissue Research

ISSN :

0302-766X

eISSN :

1432-0878

Publisher :

Springer Science & Business Media B.V., New York, United States - New York

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 05 January 2015

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52 (7 by ULiège)

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2 (2 by ULiège)

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