Reference : Poly( N-vinylcaprolactam): A thermoresponsive macromolecule with promising future in ...
Scientific journals : Article
Engineering, computing & technology : Materials science & engineering
Physical, chemical, mathematical & earth Sciences : Chemistry
http://hdl.handle.net/2268/173661
Poly( N-vinylcaprolactam): A thermoresponsive macromolecule with promising future in biomedical field
English
Liu, Ji [University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)]
Debuigne, Antoine mailto [University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)]
Detrembleur, Christophe mailto [University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)]
Jérôme, Christine mailto [University of Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)]
Dec-2014
Advanced Healthcare Materials
Wiley
3
12
1941-1968
Yes (verified by ORBi)
International
2192-2659
[en] biomaterial ; stimuli responsive polymer ; review
[en] Poly( N -vinylcaprolactam) (PNVCL) is a thermoresponsive and biocompatible polymer that raises an increasing interest in the biomedical area, especially in drug delivery systems (DDS) that include micelles, hydrogels, and hybrid particles. The thermoresponsiveness of PNVCL, used alone or in combination with other stimuli- responsive polymers or particles (pH, magnetic fi eld, or chemicals), is often key in the loading and/or release process in these DDS. The renewed focus on this polymer, which is known for decades, is to a large extent due to recent progress in synthetic strategies. Especially, the advent of efficient controlled radical polymerization (CRP) methods for NVCL monomer gives now access to unprecedented well-defi ned NVCL-based copolymers with unique properties. This Review article addresses up-to-date synthetic aspects, biological features, and biomedical applications of the latest NVCL-containing systems.
Center for Education and Research on Macromolecules (CERM)
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS ; Politique Scientifique Fédérale (Belgique) = Belgian Federal Science Policy ; The International Doctoral School "IDS-Funmat"
Researchers
http://hdl.handle.net/2268/173661
10.1002/adhm.201400371

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