Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal

[en] Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients.

Research Center/Unit :

d‐BRU - Dental Biomaterials Research Unit - ULiège

Disciplines :

General & internal medicine

Author, co-author :

Ayora, A F

HERION, Francine ; Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire

ROMPEN, Eric ; Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire

Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

Magremanne, M

LAMBERT, France ; Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire

Language :

English

Title :

Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal

Publication date :

2015

Journal title :

Journal of Clinical Periodontology

ISSN :

0303-6979

eISSN :

1600-051X

Publisher :

Wiley

Volume :

Pages :

190-195

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 21 October 2014

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