[en] Osteoporosis affects millions of elderly patients, and
anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line
therapy. Despite the benefits related to the use of these medications,
osteonecrosis of the jaw is a significant complication in a subset of patients
receiving these drugs. CASE PRESENTATION: This report documents a case of
dramatic bisphosphonate-related osteonecrosis associated with periodontitis and
dental implant removal in an osteoporotic patient treated with per os
bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of
this report was to discuss the administration period of BP in the treatment of
osteoporosis, the decision-making and clinical management of severe MRONJ and the
indications for dental implant placement in these specific patients.
Research Center/Unit :
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE]
Disciplines :
General & internal medicine
Author, co-author :
Ayora, A F
HERION, Francine ; Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire
ROMPEN, Eric ; Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire
Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Magremanne, M
LAMBERT, France ; Centre Hospitalier Universitaire de Liège - CHU > Médecine dentaire
Language :
English
Title :
Dramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
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