Article (Scientific journals)
Fiber based optofluidic biosensors
Lismont, Marjorie; Vandewalle, Nicolas; Joris, Bernard et al.
2014In Applied Physics Letters
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Keywords :
optical fibers; droplet; fluorescence; biosensor
Abstract :
[en] Medicinal diagnosis requires the development of innovative devices allowing the detection of small amounts of biological species. Among the large variety of available biosensors, the ones based on fluorescence phenomenon are really promising. Here, we show a prototype of the basic unit of a multi-sensing biosensor combining optics and microfluidics benefits. This unit makes use of two crossed optical fibers: the first fiber is used to carry small probe molecules droplets and excite fluorescence, while the second one is devoted to target molecules droplets transport and fluorescence detection. Within this scheme, the interaction takes place in each fiber node. The main benefits of this detection setup are the absence of fibers functionalization, the use of microliter volumes of target and probe species, their separation before interaction, and a better detection limit compared to cuvettes setups.
Disciplines :
Physics
Author, co-author :
Lismont, Marjorie ;  Université de Liège - ULiège > Département de physique > Biophotonique
Vandewalle, Nicolas  ;  Université de Liège - ULiège > Département de physique > Physique statistique
Joris, Bernard ;  Université de Liège - ULiège > Département des sciences de la vie > Physiologie et génétique bactériennes
Dreesen, Laurent ;  Université de Liège - ULiège > Département de physique > Biophotonique
Language :
English
Title :
Fiber based optofluidic biosensors
Publication date :
2014
Journal title :
Applied Physics Letters
ISSN :
0003-6951
eISSN :
1077-3118
Publisher :
American Institute of Physics, Melville, United States - New York
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 03 October 2014

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