Article (Scientific journals)
Effects of vitamin D in the elderly population : current status and perspectives
Bruyère, Olivier; CAVALIER, Etienne; Souberbielle, Jean-Claude et al.
2014In Archives of Public Health, 72, p. 32-42
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Abstract :
[en] Besides its well-known effect on bone metabolism, recent researches suggest that vitamin D may also play a role in the muscular, immune, endocrine, and central nervous systems. Double-blind RCTs support vitamin D supplementation at a dose of 800 IU per day for the prevention of falls and fractures in the senior population. Ecological, case–control and cohort studies have suggested that high vitamin D levels were associated with a reduced risk of autoimmune diseases, type 2 diabetes, cardio-vascular diseases and cancer but large clinical trials are lacking today to provide solid evidence of a vitamin D benefit beyond bone health. At last, the optimal dose, route of administration, dosing interval and duration of vitamin D supplementation at a specific target dose beyond the prevention of vitamin D deficiency need to be further investigated.
Disciplines :
General & internal medicine
Author, co-author :
Bruyère, Olivier  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
CAVALIER, Etienne  ;  Centre Hospitalier Universitaire de Liège - CHU > Chimie médicale
Souberbielle, Jean-Claude
Bischoff-Ferrari, HA
Beaudart, Charlotte ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Buckinx, Fanny  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Reginster, Jean-Yves  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Rizzoli, R
Language :
English
Title :
Effects of vitamin D in the elderly population : current status and perspectives
Publication date :
2014
Journal title :
Archives of Public Health
ISSN :
0778-7367
eISSN :
2049-3258
Publisher :
Scientific Institute of Public Health, Bruxelles, Belgium
Volume :
72
Pages :
32-42
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 16 September 2014

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