Article (Scientific journals)
Mapping track density changes in nigrostriatal and extranigral pathways in Parkinson's disease
Ziegler, Erik; Rouillard, Maud; André, Elodie et al.
2014In NeuroImage, 99, p. 498-508
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Keywords :
Parkinson diesease; MRI; track density
Abstract :
[en] Highlights First whole-brain probabilistic tractography study in Parkinson's disease High quality diffusion-weighted images (120 gradient directions, b = 2500 s/mm2) Voxel-based group analysis comparing early-stage patients and controls Abnormal reconstructed track density in the nigrostriatal pathway and brainstem Track density also increased in limbic and cognitive circuits.
Research center :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Author, co-author :
Ziegler, Erik ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Rouillard, Maud ;  Université de Liège - ULiège > Centre de recherches du cyclotron
André, Elodie;  Université de Liège - ULiège > Centre de recherches du cyclotron
Coolen, Tim;  Université de Liège - ULiège > Centre de recherches du cyclotron
Stender, Johan;  Université de Liège - ULiège > Centre de recherches du cyclotron
Balteau, Evelyne ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Phillips, Christophe   ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Garraux, Gaëtan   ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques
 These authors have contributed equally to this work.
Language :
English
Title :
Mapping track density changes in nigrostriatal and extranigral pathways in Parkinson's disease
Publication date :
October 2014
Journal title :
NeuroImage
ISSN :
1053-8119
eISSN :
1095-9572
Publisher :
Elsevier Science, Orlando, United States - Florida
Volume :
99
Pages :
498-508
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Fonds Rahier, ULg
Marie Curie Initial Training Network in Neurophysics (PITN-GA-2009-238593).
Available on ORBi :
since 10 August 2014

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