[en] External radiotherapy or non-steroid antiinflammatory
drugs for prevention of
heterotopic ossification following total
hip replacement
Heterotopic ossification (HO) is defined as
the development of abnormal ossification in
soft tissues. HO is a common disease after
total hip replacement. Many therapeutic modalities
have been proposed to prevent HO.
The most commonly used modalities are nonsteroidal
anti-inflammatory drugs (NSAID) or
ionizing radiation administered just before or
immediately after total hip replacement. As far
as external radiation therapy is concerned,
there are several published randomized studies
aimed at investigating its efficacy and timing
related to surgery, and at comparing ionizing
irradiation to NSAID. In this article we review
the published data in order to define guidelines
which could be used in daily practice for the
choice of prophylactic treatment against HO. [fr] Les ossifications hétérotopiques sont définies
comme une ossification des tissus mous. On les
rencontre souvent après la mise en place d’une
prothèse totale de hanche (PTH). Plusieurs modalités
thérapeutiques ont été proposées à titre
préventif pour ces ossifications hétérotopiques,
mais c’est surtout les anti-inflammatoires non
stéroïdiens (AINS) ou la radiothérapie externe
(RTH) qui semblent efficaces. En ce qui
concerne la RTH, plusieurs essais ont été conduits
qui ont permis d’en déterminer son efficacité.
Par ailleurs, on a comparé de façon directe
l’utilisation de la RTH aux AINS. Nous proposons
de revoir ces données publiées afin d’en
distiller un message clair pour les indications
cliniques des différents traitements prophylactiques.
Disciplines :
Oncology Hematology
Author, co-author :
Zouhair, A; Hospitalier Universitaire Vaudois
Ozsahin, M; Hospitalier Universitaire Vaudois
Mouhsine, E; Hôpital Orthopédique de la Suisse Normande
Leyvraz, P-F; Hôpital Orthopédique de la Suisse nORMANDE
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.