[en] OBJECTIVES: To investigate the characteristics and one-year outcomes following sirolimus-eluting CYPHER Select Plus stent (SES) implantation in small (SmVD) and non-small vessel disease (NSmVD) in the international e-SELECT registry. BACKGROUND: Large-scale registry data are lacking on DES outcomes in SmVD treatment. METHODS: There were 4,700 SmVD (at least one vessel with estimated reference vessel diameter [RVD] < 2.5 mm, excluding 283 patients with unknown RVD vessels) and 10,139 NSmVD only patients. RESULTS: The SmVD population was older, with more women, diabetics, and vessels treated, higher mean Charlson Comorbidity Index score (CCI), shorter lesions, and less STEMI presentation. The 1-year stent thrombosis (ST) rate (primary end-point), was significantly higher (1.3% vs. 0.7%) in SmVD versus NSmVD, mainly driven by early events. One-year major adverse cardiac event (MACE), myocardial infarction (MI), and clinically indicated target-lesion revascularization (TLR) rates were significantly higher in SmVD although death and major bleeding rates were similar in both groups. Complication rates were similar between pure (3,188 patients; only RVD < 2.5 mm) and mixed (1,795 patients; some RVD < 2.5 mm or unknown RVD) SmVD. Multivariate predictors for 1-year MACE in SmVD included saphenous vein graft or bifurcation lesions, major bleeding, any antiplatelet therapy discontinuation within 1 month, age, number of stents implanted, CCI, acute coronary syndrome, and insulin-dependent diabetes mellitus. CONCLUSION: SES implantation for SmVD occurs more frequently in women, diabetics, and those with multivessel disease and comorbidities. One-year ST, MACE, MI, and clinically indicated TLR rates are higher, although low overall, in SmVD or mixed SmVD patients while death rates are similar to NSmVD.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Gao, Runlin
Abizaid, Alexandre
Banning, Adrian
Bartorelli, Antonio L.
Dzavik, Vladimir
Ellis, Stephen
Jeong, Myung Ho
Legrand, Victor ; Université de Liège - ULiège > Département des sciences cliniques > Cardiologie
Spaulding, Christian
Urban, Philip
Language :
English
Title :
One-year outcome of small-vessel disease treated with sirolimus-eluting stents: a subgroup analysis of the e-SELECT registry.
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Bibliography
Biondi-Zoccai G, Moretti C, et al. Percutaneous coronary intervention for small vessel coronary artery disease. Cardiovasc Revasc Med 2010; 11: 189-198.
Bartorelli AL, Serruys PW, Miquel Hebert K, et al. An everolimus-eluting stent versus a paclitaxel-eluting stent in small vessel coronary artery disease: A pooled analysis from the SPIRIT II and SPIRIT III trials. Catheter Cardiovasc Interv 2010; 76 (1): 60-66.
Wykrzykowska JJ, Serruys PW, Onuma Y, et al. Impact of vessel size on angiographic and clinical outcomes of revascularization with biolimus-eluting stent with biodegradable polymer and sirolimus-eluting stent with durable polymer the LEADERS trial substudy. JACC Cardiovasc Interv 2009; 2 (9): 861-870.
Godino C, Furuichi S, Latib A, et al. Clinical and angiographic follow-up of small vessel lesions treated with paclitaxel-eluting stents (from the TRUE registry). Am J Cardiol 2008; 102: 1002-1008.
Colombo A, Chieffo A,. Drug-eluting stent update 2007: Part III: Technique and unapproved/unsettled indications (left main, bifurcations, chronic total occlusions, small vessels and long lesions, saphenous vein grafts, acute myocardial infarction, and multivessel disease). Circulation 2007; 116: 1424-1432.
Habara S, Mitsudo K, Goto T, et al. The impact of lesion length and vessel size on outcomes after sirolimus-eluting stent implantation for in-stent restenosis. Heart 2008; 94 (9): 1162-1165.
Hsieh IC, Chien CC, Chang HJ, et al. Acute and long-term outcomes of stenting in coronary vessel > 3.0 mm, 3.0-2.5 mm, and < 2.5 mm. Catheter Cardiovasc Interv 2001; 53: 314-322.
Süselbeck T, Latsch A, Siri H, et al. Role of vessel size as a predictor for the occurrence of in-stent restenosis in patients with diabetes mellitus. Am J Cardiol 2001; 88: 243-247.
Airoldi F, Colombo A, Morici N, et al. Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment. Circulation 2007; 116: 745-754.
Koh AS, Chia S, Choi LM, et al. Long-term outcomes after coronary bare-metal-stent and drug-eluting-stent implantations: A 'real-world' comparison among patients with diabetes with diffuse small vessel coronary artery disease. Coron Artery Dis 2011; 22 (1): 96-99.
Costa MA, Sabate M, Staico R, et al. Anatomical and physiologic assessments in patients with small coronary artery disease: Final results of the Physiologic and Anatomical Evaluation Prior to and After Stent Implantation in Small Coronary Vessels (PHANTOM) trial. Am Heart J 2007; 153 (2):296. e1-e7.
O'Connor NJ, Morton JR, Birkmeyer JD, et al. Effect of coronary artery diameter in patients undergoing coronary bypass surgery. Circulation 1996; 93: 652-655.
Cannon LA, Kereiakes DJ, Mann T, et al. A prospective evaluation of the safety and efficacy of TAXUS Element paclitaxel-eluting coronary stent implantation for the treatment of de novo coronary artery lesions in small vessels: The PERSEUS Small Vessel trial. EuroIntervention 2011; 6 (8): 920-927.
Ito H, Hermiller JB,. Percutaneous coronary intervention for small-vessel coronary disease: Highlight on the everolimus-eluting stent. Expert Rev Cardiovasc Ther 2010; 8 (9): 1239-1245.
Ortolani P, Ardissino D, Cavallini C, et al. Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy). Am J Cardiol 2005; 96 (10): 1393-1398.
Qiao SB, Hou Q, Xu B, et al. Comparison of drug-eluting stent and bare-mental stent in the complex small vessel intervention. Chin Med J (Engl) 2006; 119 (7): 596-600.
Devito FS, Sousa AG, Feres F, et al. Comparative analysis of intimal hyperplasia after sirolimus-eluting stent and thin-strut bare-metal stent implantation in small coronary arteries. Arq Bras Cardiol 2006; 86 (4): 268-275.
Ardissino D, Cavallini C, Bramucci E, et al. Sirolimus-eluting vs. uncoated stents for prevention of restenosis in small coronary arteries: A randomized trial. JAMA 2004; 292: 2727-2734.
Jabara R, Gradman M, Chen zjp, et al. Clinical and angiographic features of small vessel stenting in the drug-eluting stent era. Clin Cardiol 2009; 32 (6): e40-e45.
Tanimoto S, Daemen J, Tsuchida K, et al. Two-year clinical outcome after coronary stenting of small vessels using 2.25mm sirolimus and paclitaxel-eluting stents: Insight into the RESEARCH and T-SEARCH registries. Catheter Cardiovasc Interv 2007; 69 (1): 94-103.
Holmes DR Jr, Kereiakes DJ,. The approach to small vessels in the era of drug-eluting stents. Rev Cardiovasc Med 2005; 6 (Suppl 1): S31-S37.
Moses JW, Nikolsky E, Mehran R, et al. Safety and efficacy of the 2.25 mm sirolimus-eluting Bx Velocity stent in the treatment of patients with de novo native coronary artery lesions: The SIRIUS 2.25 trial. Am J Cardiol 2006; 98: 1455-1460.
Meier B, Sousa E, Guagliumi G, et al. Sirolimus-eluting coronary stents in small vessels. Am Heart J 2006; 151 (5):1019. e1-e7.
Hermiller JB, Fergus T, Pierson W, et al. Clinical and angiographic comparison of everolimus-eluting and paclitaxel-eluting stents in small coronary arteries: A post hoc analysis of the SPIRIT III randomized trial. Am Heart J 2009; 158 (6): 1005-1010.
Mauri L, Orav EJ, O'Malley AJ, et al. Relationship of late loss in lumen diameter to coronary restenosis in sirolimus-eluting stents. Circulation 2005; 111: 321-327.
Elezi S, Kastrati A, Neumann FJ, et al. Vessel size and long-term outcome after coronary stent placement. Circulation 1998; 98: 1875-1880.
Urban P, Abizaid A, Banning A, et al. Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population. A report from the-SELECT (multi-center post-market surveillance) registry. J Am Coll Cardiol 2011; 57 (13): 1445-1454.
Worthley SG, Abizaid A, Banning A, et al. One-year clinical outcomes after sirolimus-eluting coronary stent implantation for acute myocardial infarction in the worldwide e-SELECT registry. J Interv Cardiol 2012 Jun; 25 (3): 253-61, doi: 10.1111/j.1540-8183.2011.00705.x. Epub 2012 Feb 20.
Abizaid A, Costa JR Jr, Banning A, et al. The sirolimus-eluting Cypher Select coronary stent for the treatment of bare-metal and drug-eluting stent restenosis: Insights from the e-SELECT (Multicenter Post-Market Surveillance) registry. JACC Cardiovasc Interv 2012; 5 (1): 64-71.
Cuculi F, Banning AP, Abizaid A, et al. Outcomes in patients undergoing multivessel percutaneous coronary intervention using sirolimus-eluting stents: A report from the e-SELECT registry. Euro Intervention 2011; 7 (8): 962-968.
Hong YJ, Jeong MH, Abizaid A, et al. Sirolimus-eluting coronary stents in octogenarians: A 1-year analysis of the worldwide e-SELECT Registry. JACC Cardiovasc Interv 2011; 4 (9): 982-991.
Cutlip DE, Windecker S, Mehran R, et al. Clinical end points in coronary stent trials: A case for standardized definitions. Circulation 2007; 115: 2344-2351.
Montalescot G, White HD, Gallo R, et al. Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention. N Engl J Med 2006; 355: 1006-1017.
Charlson ME, Pompei P, Ales KL, MacKenzie CR,. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis 1987; 40: 373-383.
Biondi-Zoccai GG, Sangiorgi GM, Antoniucci D, et al. Taxus in Real-life Usage Evaluation Study. Testing prospectively the effectiveness and safety of paclitaxel-eluting stents in over 1000 very high-risk patients: Design, baseline characteristics, procedural data and in-hospital outcomes of the multicenter Taxus in Real-life Usage Evaluation (TRUE) Study. Int J Cardiol 2007; 117: 349-354.
Elezi S, Dibra A, Mehilli J, et al. Vessel size and outcome after coronary drug-eluting stent placement: Results from a large cohort of patients treated with sirolimus- or paclitaxel-eluting stents. J Am Coll Cardiol 2006; 48 (7): 1304-1309.
De Luca G, Suryapranata H, van't Hof AW, et al. Comparison between stenting and balloon angioplasty in patients undergoing primary angioplasty of small coronary vessels. Am Heart J 2006; 152 (5): 915-920.
Togni M, Eber S, Widmer J, et al. Impact of vessel size on outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents: A subgroup analysis of the SIRTAX trial. J Am Coll Cardiol 2007; 50 (12): 1123-1131.
Kastrati A, Dibra A, Mehilli J, et al. Predictive factors of restenosis after coronary implantation of sirolimus or paclitaxel eluting stents. Circulation 2006; 113 (19): 2293-2300.
Rodriguez-Granillo GA, Valgimigli M, Garcia-Garcia HM, et al. One-year clinical outcome after coronary stenting of very small vessels using 2.25 mm sirolimus and paclitaxel eluting stents: A comparison between the RESEARCH and T-SEARCH registries. J Invasive Cardiol 2005; 17 (8): 409-412.
Seabra-Gomes R, Sousa JE, Sousa A, et al. Small coronary arteries treated with sirolimus eluting stents: One-year results of the PORTO multicentre registry. Euro Intervention 2007; 3 (2): 197-205.
Mehilli J, Dibra A, Kastrati A, et al. Randomized trial of paclitaxel and sirolimus eluting stents in small coronary arteries. Eur Heart J 2006; 27: 260-266.
Li JJ, Xu B, Yang YJ, et al. Drug-eluting stent for the treatment of small coronary lesion: Comparison between sirolimus and paclitaxel eluting stent. Chin Med J (Engl) 2007; 120 (7): 569-573.
Nikolsky E, Moses JW, Mahran R, et al. Safety and efficacy of the 2.25-mm sirolimus-eluting BX Velocity stent in the treatment of patients with de novo native coronary artery lesions: the SIRIUS 2.25 trial. Am J Cardiol 2006; 98: 1455-1460.
Bucalo R, Capranzano P, Conti G, et al. Sirolimus versus paclitaxel eluting stents in small coronary vessels: Long term outcomes from a single-center registry. J Cardiovasc Med 2010; 11 (5): 365-368.
Ferrer Garcia MC, Moreno R, Pérez Vizcayno MJ, et al. Failure in the implantation of drug-eluting stents. Frequency and related factors. Med Intensiva 2007; 31: 423-427.
Stone GW, Ellis SG, Cannon L, et al. Comparison of a polymer-based paclitaxel-eluting stent with a bare metal stent in patients with complex coronary artery disease: A randomized controlled trial. JAMA 2005; 294: 1215-1223.
Schofer J, Schlüter M, Gershlick AH, et al. Sirolimus eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: Double-blind, randomised controlled trial (E-SIRIUS). Lancet 2003; 362 (9390): 1093-1099.
Schampaert E, Cohen EA, Schlüter M, et al. The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions in small native coronary arteries (C-SIRIUS). J Am Coll Cardiol 2004; 43 (6): 1110-1115.
Kaneda H, Ako J, Terashima M, et al. Sirolimus eluting stent implantation in small coronary arteries: A three dimensional intravascular ultrasound study from the SIRIUS trial. Int J Cardiol 2010; 138 (2): 126-130.
Unverdorben M, Kleber FX, Heuer H, et al. Treatment of small coronary arteries with a paclitaxel coated balloon catheter. Clin Res Cardiol 2010; 99 (3): 165-174.
Huang P, Levin T, Kabour A, et al. Acute and late outcome after use of 2.5 mm intracoronary stents in small (<2.5 mm) coronary arteries. Catheter Cardiovasc Interv 2000; 49: 121-126.
Umeda H, Iwase M, Gochi T, et al. Safety and efficacy of 2.5 mm sirolimus eluting stent implantation at lower deployment pressures in very small vessels (<2.5 mm). Coron Artery Dis 2009; 20 (2): 163-168.
Turco MA, Ormiston JA, Popma JJ, et al. Reduced risk of restenosis in small vessels and reduced risk of myocardial infarction in long lesions with the new thin-strut TAXUS Liberté stent: One-year results from the TAXUS ATLAS program. JACC Cardiovasc Interv 2008; 1 (6): 699-709.
Hausleiter J, Kastrati A, Mehilli J, et al. Predictive factors for early cardiac events and angiographic restenosis after coronary stent placement in small coronary arteries. J Am Coll Cardiol 2001; 40: 882-889.
Raisuke I, Yuji I, Akiyoshi M, et al. Predictors of restenosis after implantation of 2.5 mm stents in small coronary arteries. Circ J 2004; 68 (3): 236-240.
Iijima R, Ikari Y, Wada M, et al. Cutting balloon angioplasty is superior to balloon angioplasty or stent implantation for small coronary artery disease. Coron Artery Dis 2004; 15 (7): 435-440.
Lee CW, Suh J, Lee SW, et al. Factors predictive of cardiac events and restenosis after sirolimus-eluting stent implantation in small coronary arteries. Catheter Cardiovasc Interv 2007; 69 (6): 821-825.
Jeremias A, Sylvia B, Bridges J, et al. Stent thrombosis after successful sirolimus eluting stent implantation. Circulation 2004; 109 (16): 1930-1932.
Similar publications
Sorry the service is unavailable at the moment. Please try again later.
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.
